Amplification and overexpression of theAKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas (Q74298114)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9496907%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas (English)

1 reference

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10 November 2019

Amplification and overexpression of theAKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas (English)

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

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11 December 2024

1 reference

proto-oncogene protein

1 reference

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11 December 2024

author name string

B. A. Ruggeri

1

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11 December 2024

L. Huang

2

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11 December 2024

M. Wood

3

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11 December 2024

J. Q. Cheng

4

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11 December 2024

J. R. Testa

5

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publication date

1 February 1998

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10 November 2019

February 1998

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9496907

11 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9496907

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

11 December 2024

work available at URL

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10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

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https://onlinelibrary.wiley.com/doi/full/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

11 December 2024

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

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11 December 2024

published in

Molecular Carcinogenesis

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10 November 2019

volume

21

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10 November 2019

issue

2

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page(s)

81-86

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10 November 2019

1

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Pancreatic cancer

2

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

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Molecular Genetics of Exocrine Pancreatic Neoplasms

11 December 2024

3

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

11 December 2024

4

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Ki-ras oncogene activation in preinvasive pancreatic cancer

11 December 2024

5

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

11 December 2024

9

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer

11 December 2024

10

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

11 December 2024

11

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

11 December 2024

12

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

11 December 2024

13

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

A putative modular domain present in diverse signaling proteins

11 December 2024

14

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

The PH domain: a common piece in the structural patchwork of signalling proteins

11 December 2024

15

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

11 December 2024

16

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

11 December 2024

17

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

11 December 2024

18

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Expression and functional activity of fibroblast growth factors and their receptors in human pancreatic cancer

11 December 2024

19

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Induction of platelet‐derived growth factor A and B chains and over‐expression of their receptors in human pancreatic cancer

11 December 2024

20

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

The epidermal growth factor receptor in human pancreatic cancer

11 December 2024

21

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors

11 December 2024

22

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis

11 December 2024

23

1 reference

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

https://api.crossref.org/works/10.1002/(SICI)1098-2744(199802)21:2%3C81::AID-MC1%3E3.0.CO;2-R

11 December 2024

Identifiers

10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9496907%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference