Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114) (Q73995442)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

J M Woynarowski

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

C Napier

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

S K Koester

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

S F Chen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

D Troyer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

W Chapman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

J R MacDonald

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

language of work or name

English

0 references

publication date

1 December 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

1181-1193

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxicity

8 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Enhancement of the antitumor effect of illudin S by including it into liposomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

(Hydroxymethyl)acylfulvene: an illudin derivative with superior antitumor properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

On the mechanism of toxicity of illudins: the role of glutathione

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

XB596, a promising bis-naphthalimide anti-cancer agent.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Polymerase chain reaction analysis of cisplatin-induced mitochondrial DNA damage in human ovarian carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Effects of bizelesin (U-77779), a bifunctional alkylating minor groove agent, on genomic and simian virus 40 DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Effects of the DNA-damaging enediyne C-1027 on intracellular SV40 and genomic DNA in green monkey kidney BSC-1 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Mapping of DNA alkylation sites induced by adozelesin and bizelesin in human cells by ligation-mediated polymerase chain reaction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

The frequency of interstrand cross-links in DNA following reaction of cis-diamminedichloroplatinum(II) with cells in culture or DNA in vitro: stability of DNA cross-links and their repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

The nucleoskeleton and the topology of replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Apoptosis and cancer chemotherapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Apoptosis. Its significance in cancer and cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Apoptosis induced by microtubule disrupting drugs in cultured human lymphoma cells. Inhibitory effects of phorbol ester and zinc sulphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Features of apoptotic cells measured by flow cytometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

DNA damage, poly (ADP-ribosyl)ation and apoptotic cell death as a potential common pathway of cytotoxic drug action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Different patterns of apoptosis of HL-60 cells induced by cycloheximide and camptothecin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Inhibition of apoptosis by zinc: a reappraisal.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Apoptosis induced by DNA topoisomerase I and II inhibitors in human leukemic HL-60 cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Induction of neuronal apoptosis by excitotoxins associated with long-lasting increase of 12-O-tetradecanoylphorbol 13-acetate-responsive element-binding activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Bleomycin-induced aggregation of presolubilized and nuclear chromatin from L1210 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

Induction of DNA-protein crosslinks by antitumor 1-nitro-9-aminoacridines in L1210 leukemia cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

inferred from DOI database lookup

7 January 2021

based on heuristic

Kinetics of apoptosis and secondary necrosis in cultured rat thymocytes and S.49 mouse lymphoma and CEM human leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900321-3

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(97)00321-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9416969%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference