TGF-beta1 production in inflammatory bowel disease: differing production patterns in Crohn's disease and ulcerative colitis (Q73943090)

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8 November 2019

title

TGF-beta1 production in inflammatory bowel disease: differing production patterns in Crohn's disease and ulcerative colitis (English)

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8 November 2019

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inflammatory bowel diseases

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B Del Zotto

1

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8 November 2019

G Mumolo

2

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8 November 2019

A M Pronio

3

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8 November 2019

C Montesani

4

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8 November 2019

R Tersigni

5

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8 November 2019

M Boirivant

6

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8 November 2019

publication date

1 October 2003

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Clinical and Experimental Immunology

8 November 2019

published in

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8 November 2019

volume

134

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8 November 2019

issue

1

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8 November 2019

page(s)

120-126

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Reciprocal IFN-gamma and TGF-beta responses regulate the occurrence of mucosal inflammation

8 November 2019

cites work

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12 December 2020

High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-beta secretion and T cell apoptosis

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Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

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CD4+ T cell down-regulation in human intestinal mucosa: evidence for intestinal tolerance to luminal bacterial antigens.

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TGFbeta1 regulates gene expression of its own converting enzyme furin

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene

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12 December 2020

Regulation of immune responses by TGF-beta

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12 December 2020

Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production.

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12 December 2020

Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4.

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12 December 2020

Transforming growth factor-betas and their signaling receptors are coexpressed in Crohn's disease

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12 December 2020

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

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12 December 2020

T cell specificity and cross reactivity towards enterobacteria, bacteroides, bifidobacterium, and antigens from resident intestinal flora in humans

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12 December 2020

Site-specific changes in transforming growth factor-alpha and -beta1 expression in colonic mucosa of adolescents with inflammatory bowel disease

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12 December 2020

Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease.

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TGF-beta: from latent to active

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A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA

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Modulation of transforming growth factor beta-1 gene expression by interleukin-12.

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Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression.

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Involvement of Smads in TGFbeta1-induced furin (fur) transcription

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12 December 2020

Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

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12 December 2020

IL-4-mediated development of TGF-beta1-producing cells from naïve CD4(+) T cells through a STAT6-independent mechanism

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12 December 2020

Transforming growth factor-beta in T-cell biology

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12 December 2020

Isolation and functional characterization of human intestinal mucosal lymphoid cells

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12 December 2020

Spontaneous release of interferon gamma by intestinal lamina propria lymphocytes in Crohn's disease. Kinetics of in vitro response to interferon gamma inducers

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12 December 2020

Interleukin-2- and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa

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12 December 2020

Processing of transforming growth factor beta 1 precursor by human furin convertase

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12 December 2020

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

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12 December 2020

Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease

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12 December 2020

Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance

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12 December 2020

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

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12 December 2020

Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients

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12 December 2020

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

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12 December 2020