Multistep renal carcinogenesis as gene expression disease in tumor suppressor TSC2 gene mutant model--genotype, phenotype and environment (Q73934715)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11376696%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Multistep renal carcinogenesis as gene expression disease in tumor suppressor TSC2 gene mutant model--genotype, phenotype and environment (English)

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7 November 2019

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O Hino

1

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7 November 2019

S Majima

2

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7 November 2019

T Kobayashi

3

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7 November 2019

S Honda

4

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7 November 2019

S Momose

5

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7 November 2019

Y Kikuchi

6

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7 November 2019

H Mitani

7

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7 November 2019

language of work or name

English

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publication date

1 June 2001

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7 November 2019

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7 November 2019

volume

477

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7 November 2019

issue

1-2

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7 November 2019

page(s)

155-164

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Mutation and cancer: statistical study of retinoblastoma

7 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

TSC2 gene mutant (Eker) rat model of a Mendelian dominantly inherited cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

A Dominant Gene for Renal Adenomas in the Rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Universal mapping probes and the origin of human chromosome 3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

A novel renal cell carcinoma susceptibility gene maps on chromosome 10 in the Eker rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Predisposition to renal cell carcinoma due to alteration of a cancer susceptibility gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-type Tsc2 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

A novel cancer predisposition syndrome in the Eker rat model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Allelic loss at the tuberous sclerosis (Tsc2) gene locus in spontaneous uterine leiomyosarcomas and pituitary adenomas in the Eker rat model.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Novel cerebral lesions in the Eker rat model of tuberous sclerosis: cortical tuber and anaplastic ganglioglioma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Intragenic Tsc2 somatic mutations as Knudson's second hit in spontaneous and chemically induced renal carcinomas in the Eker rat model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Identification and characterization of the tuberous sclerosis gene on chromosome 16

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

cDNA structure, alternative splicing and exon-intron organization of the predisposing tuberous sclerosis (Tsc2) gene of the Eker rat model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Identification of a leader exon and a core promoter for the rat tuberous sclerosis 2 (Tsc2) gene and structural comparison with the human homolog.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

A de novo frame-shift mutation in the tuberin gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Distribution of Tsc1 protein detected by immunohistochemistry in various normal rat tissues and the renal carcinomas of Eker rat: detection of limited colocalization with Tsc1 and Tsc2 gene products in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Isolation of genes differentially expressed between the Yoshida sarcoma and long-survival Yoshida sarcoma variants: origin of Yoshida sarcoma revisited

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Renal carcinogenesis in the Eker rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Identification of cDNAs induced by the tumor suppressor Tsc2 gene using a conditional expression system in Tsc2 mutant (Eker) rat renal carcinoma cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Overexpression of members of the AP-1 transcriptional factor family from an early stage of renal carcinogenesis and inhibition of cell growth by AP-1 gene antisense oligonucleotides in the Tsc2 gene mutant (Eker) rat model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Mapping and determination of the cDNA sequence of the Erc gene preferentially expressed in renal cell carcinoma in the Tsc2 gene mutant (Eker) rat model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

A novel gene "Niban" upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Localization of the interferon-alpha gene cluster to rat chromosome bands 5q31----q33 by fluorescence in situ hybridization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Generation of metastatic variants of Eker renal carcinoma cell lines for experimental investigation of renal cancer metastasis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Somatic mutation of the tuberous sclerosis (Tsc2) tumor suppressor gene in chemically induced rat renal carcinoma cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Biallelic mutations of the Tsc2 gene in chemically induced rat renal cell carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Cloning of the rat homologue of the von Hippel-Lindau tumor suppressor gene and its non-somatic mutation in rat renal cell carcinomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

A novel "Nihon" rat model of a Mendelian dominantly inherited renal cell carcinoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

TNF-alpha gene expression in the liver of the IFN-gamma transgenic mouse with chronic active hepatitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2801%2900116-6

10.1016/S0027-5107(01)00116-6

7 January 2021

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DOI

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7 November 2019

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