Double-positive T cell receptor(high) thymocytes are resistant to peptide/major histocompatibility complex ligand-induced negative selection (Q73814879)

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scientific article published on 01 September 1997

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English	Double-positive T cell receptor(high) thymocytes are resistant to peptide/major histocompatibility complex ligand-induced negative selection	scientific article published on 01 September 1997

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scholarly article

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6 November 2019

Double-positive T cell receptor(high) thymocytes are resistant to peptide/major histocompatibility complex ligand-induced negative selection (English)

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6 November 2019

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author name string

Ghendler Y

1

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Hussey RE

2

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Witte T

3

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Mizoguchi E

4

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Clayton LK

5

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Bhan AK

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Chang HC

8

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Reinherz EL

9

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publication date

1 September 1997

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European Journal of Immunology

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9

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2279-2289

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6 November 2019

A third type of murine T-cell receptor gene

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Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

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A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

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Sequence and expression of transcripts of the human T-cell receptor beta-chain genes.

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T-cell antigen receptor genes and T-cell recognition

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Molecular and cellular events of T cell development

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Negative selection of lymphocytes

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In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

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On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

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Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

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Positive selection of lymphocytes

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Positive selection of T cells

1 reference

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7 January 2021

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Positive selection of thymocytes

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Selective inhibition of interleukin 2 gene function following thymocyte antigen/major histocompatibility complex receptor crosslinking: possible thymic selection mechanism

1 reference

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T cell tolerance by clonal elimination in the thymus

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Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

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Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

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In vivo and in vitro clonal deletion of double-positive thymocytes

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Positive and negative thymocyte selection induced by different concentrations of a single peptide

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Evidence for a differential avidity model of T cell selection in the thymus

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T cell receptor antagonist peptides induce positive selection

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Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice

1 reference

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The effects of MHC gene dosage and allelic variation on T cell receptor selection

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Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

1 reference

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Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

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Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities

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ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

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The kinetics of T cell antigen receptor expression by subgroups of CD4+8+ thymocytes: delineation of CD4+8+3(2+) thymocytes as post-selection intermediates leading to mature T cells

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Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor.

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Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

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Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

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T-cell apoptosis detected in situ during positive and negative selection in the thymus

1 reference

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Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody

1 reference

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Specificity and flexibility in thymic selection

1 reference

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Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

1 reference

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7 January 2021

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Mature T cell reactivity altered by peptide agonist that induces positive selection

1 reference

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7 January 2021

based on heuristic

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Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

1 reference

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based on heuristic

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Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes

1 reference

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based on heuristic

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Ligands for the T-cell receptor: hard times for avidity models

1 reference

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based on heuristic

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T cell receptor antagonists and partial agonists

1 reference

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based on heuristic

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Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

1 reference

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based on heuristic

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1 reference

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based on heuristic

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T-cell-receptor affinity and thymocyte positive selection

1 reference

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based on heuristic

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Negative selection of precursor thymocytes before their differentiation into CD4+CD8+ cells

1 reference

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7 January 2021

based on heuristic

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Developmental regulation of thymocyte susceptibility to deletion by "self"-peptide

1 reference

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based on heuristic

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Residues of the variable region of the T-cell-receptor β-chain that interact with S. aureus toxin superantigens

1 reference

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based on heuristic

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Identification of the region of T cell receptor β chain that interacts with the self-superantigen MIs-1a

1 reference

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Superantigen binding to a T cell receptor beta chain of known three-dimensional structure

1 reference

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based on heuristic

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Activation of polyphosphoinositide hydrolysis in T cells by H-2 alloantigen but not MLS determinants

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)

1 reference

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The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1 reference

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ICE family proteases: mediators of all apoptotic cell death?

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Identifiers

10.1002/EJI.1830270923

1 reference

Europe PubMed Central

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6 November 2019

1 reference

Europe PubMed Central

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6 November 2019

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