Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation (Q73648579)

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scientific article published on 01 September 1997

Language	Label	Description	Also known as
English	Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation	scientific article published on 01 September 1997

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278451%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278451%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

P Berhanu

1

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5 November 2019

C Anderson

2

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5 November 2019

M Hickman

3

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5 November 2019

T P Ciaraldi

4

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publication date

1 September 1997

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5 November 2019

Journal of Biological Chemistry

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5 November 2019

272

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5 November 2019

36

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5 November 2019

22884-22890

1 reference

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5 November 2019

Insulin receptor substrate 1 and 2 (IRS1 and IRS2): what a tangled web we weave.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

The NPEY Sequence Is Not Necessary for Endocytosis and Processing of Insulin-Receptor Complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Cytoplasmic juxtamembrane region of the insulin receptor: a critical role in ATP binding, endogenous substrate phosphorylation, and insulin-stimulated bioeffects in CHO cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

In vitro effects of amylin on carbohydrate metabolism in liver cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Crystal structure of the tyrosine kinase domain of the human insulin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Effect of phosphotyrosyl-IRS-1 level and insulin receptor tyrosine kinase activity on insulin-stimulated phosphatidylinositol 3, MAP, and S6 kinase activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Enhancement or inhibition of insulin signaling by insulin receptor substrate 1 is cell context dependent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

The B isoform of the insulin receptor signals more efficiently than the A isoform in HepG2 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.36.22884

21 January 2018

Identifiers

10.1074/JBC.272.36.22884

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278451%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9278451%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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