NB-506, an indolocarbazole topoisomerase I inhibitor, binds preferentially to triplex DNA (Q73616669)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

NB-506, an indolocarbazole topoisomerase I inhibitor, binds preferentially to triplex DNA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

J Ren

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

C Bailly

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

publication date

1 March 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

470

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

355-359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

A new antitumor substance, BE-13793C, produced by a streptomycete. Taxonomy, fermentation, isolation, structure determination and biological activity

5 November 2019

cites work

2 references

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

21 January 2018

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Production and biological activity of rebeccamycin, a novel antitumor agent.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Antimetastatic effect of a novel indolocarbazole (NB-506) on IMC-HM murine tumor cells metastasized to the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

New chemotherapeutic agents for the treatment of non-small cell lung cancer: the Japanese experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Molecular Anchoring of Duplex and Triplex DNA by Disubstituted Anthracene-9,10-diones: Calorimetric, UV Melting, and Competition Dialysis Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Sequence and structural selectivity of nucleic acid binding ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Interactions of heteroaromatic compounds with nucleic acids. 1. The influence of heteroatoms and polarizability on the base specificity of intercalating ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Bromination stabilizes poly(dG-dC) in the Z-DNA form under low-salt conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

The interaction of intercalators and groove-binding agents with DNA triple-helical structures: the influence of ligand structure, DNA backbone modifications and sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Stability and structure of model DNA triplexes and quadruplexes and their interactions with small ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Triple helix-specific ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Energetics of drug-DNA interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Ethidium binding to left-handed (Z) DNAs results in regions of right-handed DNA at the intercalation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

Interaction of drugs with Z-DNA: cooperative binding of actinomycin D or actinomine to the left-handed forms of poly(dG-dC).poly(dG-dC) and poly(dG-m5dC).poly(dG-m5dC) reverses the conformation of the helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2901335-1

10.1016/S0014-5793(00)01335-1

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10745096%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference