Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro (Q73595089)

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5 November 2019

title

Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro (English)

1 reference

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5 November 2019

main subject

lymphoblastic leukemia

1 reference

3

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5 November 2019

author name string

J Juarez

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12835717%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

K F Bradstock

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12835717%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

L J Bendall

series ordinal

4

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5 November 2019

publication date

1 July 2003

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5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12835717%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

17

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5 November 2019

issue

7

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5 November 2019

page(s)

1294-1300

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402998

5 November 2019

exact match

0 references

cites work

Effects of the chemokine stromal cell-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromal layers.

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Molecular cloning and structure of a pre-B-cell growth-stimulating factor

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Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

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7 January 2021

The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow.

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7 January 2021

Survival of human leukaemic B-cell precursors is supported by stromal cells and cytokines: association with the expression of bcl-2 protein

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7 January 2021

N-terminal peptides of stromal cell-derived factor-1 with CXC chemokine receptor 4 agonist and antagonist activities

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Effective lowly cytotoxic analogs of an HIV-cell fusion inhibitor, T22 ([Tyr5,12, Lys7]-polyphemusin II).

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Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4

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Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers

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AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice.

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The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4.

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7 January 2021

Maturation decreases responsiveness of human bone marrow B lineage cells to stromal-derived factor 1 (SDF-1)

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SDF-1-induced actin polymerization and migration in human hematopoietic progenitor cells

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Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines

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7 January 2021

Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140.

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