Inhibition of growth of MDA-MB-468 estrogen-independent human breast carcinoma by bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II (Q73549635)

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scientific article published on 01 March 2000

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English	Inhibition of growth of MDA-MB-468 estrogen-independent human breast carcinoma by bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II	scientific article published on 01 March 2000

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scholarly article

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4 November 2019

Inhibition of growth of MDA-MB-468 estrogen-independent human breast carcinoma by bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II (English)

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4 November 2019

breast carcinoma

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based on heuristic

inferred from title

3

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4 November 2019

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Z Kahán

1

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B Sun

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4 November 2019

J M Arencibia

4

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4 November 2019

R Z Cai

5

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K Groot

6

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G Halmos

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publication date

1 March 2000

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4 November 2019

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4 November 2019

88

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4 November 2019

6

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4 November 2019

1384-1392

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4 November 2019

Cancer statistics, 1998.

1 reference

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21 January 2018

Recent advances in systemic therapy for breast cancer

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Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

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Enhanced expression of neuropeptides in human breast cancer cell lines following irradiation

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Cloning of a receptor for amphibian [Phe13]bombesin distinct from the receptor for gastrin-releasing peptide: identification of a fourth bombesin receptor subtype (BB4)

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Growth inhibition of estrogen-dependent and estrogen-independent MXT mammary cancers in mice by the bombesin and gastrin-releasing peptide antagonist RC-3095

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Inhibitory effect of bombesin/gastrin-releasing peptide (GRP) antagonists RC-3950-II and RC-3095 on MCF-7 MIII human breast cancer xenografts in nude mice

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Inhibition of growth of MDA-MB-231 human breast cancer xenografts in nude mice by bombesin/gastrin-releasing peptide (GRP) antagonists RC-3940-II and RC-3095.

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Characterization, in some human breast cancer cell lines, of gastrin-releasing peptide-like receptors which are absent in normal breast epithelial cells

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Bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II inhibit tumor growth and decrease the levels and mRNA expression of epidermal growth factor receptors in H-69 small cell lung carcinoma

1 reference

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21 January 2018

Inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist Cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II.

1 reference

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21 January 2018

Luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75) and bombesin antagonist RC-3940-II inhibit the growth of androgen-independent PC-3 prostate cancer in nude mice

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21 January 2018

Inhibition of the growth of Caki-I human renal adenocarcinoma in vivo by luteinizing hormone-releasing hormone antagonist Cetrorelix, somatostatin analog RC-160, and bombesin antagonist RC-3940-II.

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Antagonists of bombesin/gastrin-releasing peptide inhibit growth of SW-1990 human pancreatic adenocarcinoma and production of cyclic AMP

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Synergistic effects of bombesin and epidermal growth factor on cancers

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Epidermal growth factor regulates the expression of its own receptor

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21 January 2018

Reduction in receptors for bombesin and epidermal growth factor in xenografts of human small-cell lung cancer after treatment with bombesin antagonist RC-3095.

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21 January 2018

MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGF.

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LIGAND: A versatile computerized approach for characterization of ligand-binding systems

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Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates that it has a unique pharmacology compared with other mammalian bombesin receptors

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Effects of somatostatin analogue RC-160 and bombesin/gastrin-releasing peptide antagonists on the growth of human small-cell and non-small-cell lung carcinomas in nude mice

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Expression of mRNA for three bombesin receptor subtypes in human bronchial epithelial cells

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A single in vivo administration of bombesin antagonist RC-3095 reduces the levels and mRNA expression of epidermal growth factor receptors in MXT mouse mammary cancers

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Epidermal Growth Factor

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21 January 2018

Identifiers

10.1002/(SICI)1097-0142(20000315)88:6<1384::AID-CNCR16>3.0.CO;2-Q

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10717621%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10717621%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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