MYCN Amplification in Neuroblastoma: a Paradigm for the Clinical Use of an Oncogene (Q73429805)

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3 November 2019

title

MYCN Amplification in Neuroblastoma: a Paradigm for the Clinical Use of an Oncogene (English)

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3 November 2019

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Manfred Schwab

1

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3 November 2019

publication date

1 January 1997

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Pathology Oncology Research

3 November 2019

published in

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3 November 2019

volume

3

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3 November 2019

issue

1

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3 November 2019

page(s)

3-7

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https://scigraph.springernature.com/pub.10.1007/bf02893344

3 November 2019

exact match

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cites work

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

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12 December 2020

Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA.

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12 December 2020

Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc

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12 December 2020

A reciprocal translocation (1;15) (36.2;q24) in a neuroblastoma cell line is accompanied by DNA duplication and may signal the site of a putative tumor suppressor-gene.

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12 December 2020

Suppression of MYC by high expression of NMYC in human neuroblastoma cells

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12 December 2020

Translocation involving 1p and 17q is a recurrent genetic alteration of human neuroblastoma cells.

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12 December 2020

Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma

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12 December 2020

MYCN is retained in single copy at chromosome 2 band p23-24 during amplification in human neuroblastoma cells

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12 December 2020

Oncogene amplification in tumor cells.

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12 December 2020

The MYCN protein of human neuroblastoma cells is phosphorylated by casein kinase II in the central region and at serine 367

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12 December 2020

Patterns of oncogene activation in human neuroblastoma cells

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12 December 2020

Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells.

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12 December 2020

The N-Myc oncoprotein is associated in vivo with the phosphoprotein Max(p20/22) in human neuroblastoma cells

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12 December 2020

Translocation junctions cluster at the distal short arm of chromosome 1 (1p36.1-2) in human neuroblastoma cells

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12 December 2020

Chromosome 1 deletions in human neuroblastomas: generation and fine mapping of microclones from the distal 1p region

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12 December 2020

Activation of gene transcription by the amino terminus of the N-Myc protein does not require association with the protein encoded by the retinoblastoma suppressor gene RB1.

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12 December 2020

Amplification of cellular oncogenes: a predictor of clinical outcome in human cancer

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12 December 2020

Genomic instability in 1p and human malignancies

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12 December 2020

Non-syntenic amplification of MDM2 and MYCN in human neuroblastoma

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12 December 2020

Neuroblastoma consensus deletion maps to 1p36.1-2.

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12 December 2020

Localization of regulatory elements controlling human MYCN expression

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12 December 2020

Duplication of N-MYC at its resident site 2p24 may be a mechanism of activation alternative to amplification in human neuroblastoma cells

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12 December 2020

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

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12 December 2020

Identifiers

DOI

10.1007/BF02893344

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11173617%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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