The Epithelial-Specific ETS Transcription Factor ESX/ESE-1/Elf-3 Modulates Breast Cancer-Associated Gene Expression (Q73314803)

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3 November 2019

title

The epithelial-specific ETS transcription factor ESX/ESE-1/Elf-3 modulates breast cancer-associated gene expression (English)

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3 November 2019

The Epithelial-Specific ETS Transcription Factor ESX/ESE-1/Elf-3 Modulates Breast Cancer-Associated Gene Expression (English)

1 reference

https://api.crossref.org/works/10.1089/104454903321515896

neoplastic gene expression regulation

27 December 2023

main subject

1 reference

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transcriptional activation

27 December 2023

1 reference

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27 December 2023

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27 December 2023

author name string

Arthur Gutierrez-Hartmann

5

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3 November 2019

Kristin L. Eckel

1

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John J. Tentler

2

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27 December 2023

Gerald J. Cappetta

3

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27 December 2023

Scott E. Diamond

4

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language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12713734

27 December 2023

publication date

1 February 2003

1 reference

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full work available at URL

3 November 2019

http://www.liebertpub.com/doi/pdf/10.1089/104454903321515896

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27 December 2023

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3 November 2019

volume

22

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3 November 2019

issue

2

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3 November 2019

page(s)

79-94

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Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter

3 November 2019

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Expression of the PEA3 group of ETS-related transcription factors in human breast-cancer cells

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HER2/Neu and the Ets transcription activator PEA3 are coordinately upregulated in human breast cancer.

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Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression

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ESX: a structurally unique Ets overexpressed early during human breast tumorigenesis

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Exon 4-encoded acidic domain in the epithelium-restricted Ets factor, ESX, confers potent transactivating capacity and binds to TATA-binding protein (TBP)

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Secondary structure of the ETS domain places murine Ets-1 in the superfamily of winged helix-turn-helix DNA-binding proteins.

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Elevated expression of Ets2 or distinct portions of Ets2 can reverse Ras-mediated cellular transformation

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Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation

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Expression of c-ets-1 mRNA is associated with an invasive, EMT-derived phenotype in breast carcinoma cell lines

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Pit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin beta-subunit promoter

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Distinct protein targets for signals acting at the c-fos serum response element

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Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression

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Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12713734%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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