The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production (Q73310082)

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scientific article published on 01 December 2000

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English	The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production	scientific article published on 01 December 2000

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scholarly article

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2 November 2019

The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production (English)

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2 November 2019

experimental autoimmune encephalomyelitis

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prostaglandin E2

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based on heuristic

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author name string

L S Harbige

1

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2 November 2019

L Layward

2

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2 November 2019

M M Morris-Downes

3

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2 November 2019

D C Dumonde

4

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2 November 2019

S Amor

5

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publication date

1 December 2000

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2 November 2019

Clinical and Experimental Immunology

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2 November 2019

122

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2 November 2019

3

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2 November 2019

445-452

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2 November 2019

A new view of prostaglandin E regulation of the immune response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of endogenous regulatory function of transforming growth factor-beta 1 in experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor beta1 (TGFbeta1) mRNA level correlates with magnetic resonance imaging disease activity in multiple sclerosis patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progress in determining the causes and treatment of multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple method for the isolation and purification of total lipides from animal tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4,

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a major encephalitogenic epitope of proteolipid protein (residues 56-70) for the induction of experimental allergic encephalomyelitis in Biozzi AB/H and nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the mechanisms by which transforming growth factor-beta (TGF-beta) protects against allergic encephalomyelitis. Antagonism between TGF-beta and tumor necrosis factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta suppresses activation and proliferation of microglia in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid induction and clearance of TGF beta 1 is an early response to wounding in the mouse embryo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential fatty acids alter the activity of manganese-superoxide dismutase in rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased TGF-beta and decreased oncogene expression by omega-3 fatty acids in the spleen delays onset of autoimmune disease in B/W mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective production of anti-inflammatory cytokine, TGF-beta by T cell lines of patients with active multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of prostaglandin E2 on Th0-type human T cell clones: modulation of functions of nuclear proteins involved in cytokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine mRNA levels in mononuclear blood cells from patients with multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific T-cell tolerance may reflect selective activation of lymphokine synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon gamma, interleukin 4 and transforming growth factor beta in experimental autoimmune encephalomyelitis in Lewis rats: dynamics of cellular mRNA expression in the central nervous system and lymphoid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids, dietary lipids and lymphocyte functions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of experimental autoimmune encephalomyelitis in Lewis rats by a novel fungal source of gamma-linolenic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between adipose tissue and the immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of immune injury in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of omega-6 lipid-rich borage oil feeding on immune function in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine secretion by human T cell clones is differentially regulated by eicosanoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary fatty acids and lymphocyte functions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary n-6 and n-3 fatty acids in immunity and autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allergic encephalomyelitis induced by brain antigen after deficiency in polyunsaturated fatty acids during myelination. Is multiple sclerosis a nutritive disorder?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid composition of phospholipids from platelets and erythrocytes in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific Inhibitory Action of Polyunsaturated Fatty Acids on Lymphocyte Transformation Induced by PHA and PPD

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fat Deficiency in Rats during Development of the Central Nervous System and Susceptibility to Experimental Allergic Encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction by linoleic acid of the severity of experimental allergic encephalomyelitis in the guinea pig

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression by essential fatty acids of experimental allergic encephalomyelitis is abolished by indomethacin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The spleen is required for the suppression of experimental allergic encephalomyelitis by prostaglandin precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levels of linoleate and arachidonate in red blood cells of healthy individuals and patients with multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linoleic acid therapy in severe experimental allergic encephalomyelitis in the guinea-pig: suppression by continuous treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of indomethacin treatment upon actively-induced and transferred experimental allergic encephalomyelitis (EAE) in Lewis rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

"A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linoleic acid and multiple sclerosis: a reanalysis of three double-blind trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutrition and immunity: the immunoregulatory effect of n-6 essential fatty acids is mediated through prostaglandin E.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a major encephalitogenic T cell epitope in SJL/J mice with synthetic oligopeptides of myelin basic protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Red blood cell fatty acids in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ suppressor cells inhibit the function of effector cells of experimental autoimmune encephalomyelitis through a mechanism involving transforming growth factor-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta-like activity produced during regression of exacerbations in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11122253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2249.2000.01399.X

1 reference

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2 November 2019

0 references

1 reference

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2 November 2019

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