An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia (Q73263703)

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scientific article published on 01 December 1999

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English	An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia	scientific article published on 01 December 1999

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10594073%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia (English)

1 reference

Europe PubMed Central

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2 November 2019

blood–brain barrier

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inferred from title

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based on heuristic

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author name string

N Laflamme

1

1 reference

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2 November 2019

S Lacroix

2

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2 November 2019

S Rivest

3

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2 November 2019

publication date

1 December 1999

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2 November 2019

Journal of Neuroscience

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2 November 2019

19

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2 November 2019

24

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2 November 2019

10923-10930

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2 November 2019

Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of prostaglandin synthesis responsible for fever

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

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inferred from PubMed ID database lookup

Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

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Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

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Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

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Induction of inhibitory factor kappaBalpha mRNA in the central nervous system after peripheral lipopolysaccharide administration: an in situ hybridization histochemistry study in the rat

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https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

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NF-kappa B: ten years after

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https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

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Bacterial toxin-induced cytokine production studied at the single-cell level

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

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Electron microscopic evidence for induction of cyclooxygenase-2 in brain endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide stimulates the tyrosine phosphorylation of mitogen-activated protein kinases p44, p42, and p41 in vascular endothelial cells in a soluble CD14-dependent manner. Role of protein tyrosine phosphorylation in lipopolysaccharide-induce

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammatory response in interleukin-1 beta-deficient mice: comparison with other cytokine-related knock-out mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain endothelial cells express cyclooxygenase-2 during lipopolysaccharide-induced fever: light and electron microscopic immunocytochemical studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

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Cyclooxygenase 2 mRNA expression in rat brain after peripheral injection of lipopolysaccharide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

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Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basal expression of cyclooxygenase-2 and nuclear factor-interleukin 6 are dominant and coordinately regulated by interleukin 1 in the pancreatic islet

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-inflammatory signaling: last pieces in the NF-kappaB puzzle?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

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Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

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Characterization of tumor necrosis factor-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

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A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of acute systemic inflammatory response and cytokines on the transcription of the genes encoding cyclooxygenase enzymes (COX-1 and COX-2) in the rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide injected into the cerebral ventricle evokes fever through induction of cyclooxygenase-2 in brain endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

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Mechanisms of CNS response to systemic immune challenge: the febrile response

1 reference

https://pubmed.ncbi.nlm.nih.gov/10594073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.19-24-10923.1999

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10594073%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10594073%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10594073%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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