Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate (Q73130894)

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scientific article published on 01 February 1997

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English	Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate	scientific article published on 01 February 1997

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scholarly article

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1 November 2019

Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate (English)

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1 November 2019

Giuseppina Di Stefano

2

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1 November 2019

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L Fiume

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1 November 2019

C Busi

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1 November 2019

A Mattioli

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1 November 2019

G Battista Gervasi

5

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1 November 2019

M Bertini

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1 November 2019

C Bartoli

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1 November 2019

R Catalani

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1 November 2019

G Caccia

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1 November 2019

C Farina

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1 November 2019

A Fissi

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1 November 2019

O Pieroni

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1 November 2019

R Giuseppetti

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1 November 2019

E D'Ugo

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1 November 2019

R Bruni

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1 November 2019

M Rapicetta

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1 November 2019

publication date

1 February 1997

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1 November 2019

Journal of Hepatology

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1 November 2019

26

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1 November 2019

2

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1 November 2019

253-259

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1 November 2019

Enhanced inhibition of virus DNA synthesis in hepatocytes by trifluorothymidine coupled to asialofetuin

1 reference

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7 January 2021

based on heuristic

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Selective inhibition of ectromelia virus DNA synthesis in hepatocytes by adenine-9-β-D-arabinofuranoside (ara-A) and adenine-9-β-D-arabinofuranoside 5′-monophosphate (ara-AMP) conjugated to asialofetuin

1 reference

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7 January 2021

based on heuristic

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Hepatocyte targeting of adenine-9-beta-D-arabinofuranoside 5' -monophosphate (ara-AMP) coupled to lactosaminated albumin

1 reference

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7 January 2021

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Drug targeting in antiviral chemotherapy. A chemically stable conjugate of 9-beta-D-arabinofuranosyl-adenine 5'-monophosphate with lactosaminated albumin accomplishes a selective delivery of the drug to liver cells

1 reference

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7 January 2021

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Galactosylated poly(L-lysine) as a hepatotropic carrier of 9-beta-D-arabinofuranosyladenine 5'-monophosphate

1 reference

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7 January 2021

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Inhibition of hepatitis B virus replication by vidarabine monophosphate conjugated with lactosaminated serum albumin.

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Inhibition of hepatitis B virus replication by adenine arabinoside monophosphate coupled to lactosaminated albumin. Efficacy and minimal active dose.

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7 January 2021

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Adenine arabinoside monophosphate coupled to lactosaminated human albumin administered for 4 weeks in patients with chronic type B hepatitis decreased viremia without producing significant side effects

1 reference

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7 January 2021

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Adenine arabinoside 5'-monophosphate in patients with chronic hepatitis B: comparison of the efficacy in patients with high and low viral replication.

1 reference

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7 January 2021

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Specific targeting of the antiviral drug 5-iodo 2'-deoxyuridine to the parenchymal liver cell using lactosylated poly-L-lysine

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7 January 2021

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A conjugate of lactosaminated poly-L-lysine with adenine arabinoside monophosphate, administered to mice by intramuscular route, accomplishes a selective delivery of the drug to the liver

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Selective delivery to the liver of antiviral nucleoside analogs coupled to a high molecular mass lactosaminated poly-L-lysine and administered to mice by intramuscular route.

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The determination of the molecular weight of poly-L-lysine

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Proteins containing reductively aminated disaccharides. Synthesis and chemical characterization

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[50] Protein labeling by reductive alkylation

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A PCR-based strategy for rapid mapping of hepadnavirus integrated sequences in hepatocellular carcinomas

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Renal filtration, transport, and metabolism of low-molecular-weight proteins: A review

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Abnormal surface distribution of the human asialoglycoprotein receptor in cirrhosis

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Adenine arabinoside monophosphate and acyclovir monophosphate coupled to lactosaminated albumin reduce woodchuck hepatitis virus viremia at doses lower than do the unconjugated drugs

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The pathogenesis of vacuoles produced in rat and mouse liver cells by a conjugate of adenine arabinoside monophosphate with lactosaminated albumin

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Identifiers

10.1016/S0168-8278(97)80038-4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9059943%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9059943%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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