Inhibitory mechanism of serpins. Mobility of the C-terminal region of the reactive-site loop (Q73038969)

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31 October 2019

title

Inhibitory mechanism of serpins. Mobility of the C-terminal region of the reactive-site loop (English)

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31 October 2019

author name string

P C Hopkins

1

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31 October 2019

W S Chang

2

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31 October 2019

M R Wardell

3

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31 October 2019

S R Stone

4

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31 October 2019

language of work or name

English

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publication date

1 February 1997

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Journal of Biological Chemistry

31 October 2019

published in

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31 October 2019

volume

272

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31 October 2019

issue

7

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31 October 2019

page(s)

3905-3909

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Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

31 October 2019

cites work

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Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins

21 January 2018

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Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

21 January 2018

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Synthesis of pppGpN typs dinucleotide derivatives: the 5′ end sequence of some RNAs

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Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI

21 January 2018

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Natural protein proteinase inhibitors and their interaction with proteinases

21 January 2018

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Modeling studies of the change in conformation required for cleavage of limited proteolytic sites

21 January 2018

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Modeling the intact form of the alpha 1-proteinase inhibitor.

21 January 2018

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Structural basis for serpin inhibitor activity

21 January 2018

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The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

21 January 2018

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Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

21 January 2018

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Effects of mutations in the hinge region of serpins

21 January 2018

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Alpha 1-proteinase inhibitor variant T345R. Influence of P14 residue on substrate and inhibitory pathways

21 January 2018

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Pleiotropic effects of antithrombin strand 1C substitution mutations

21 January 2018

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COOH-terminal substitutions in the serpin C1 inhibitor that cause loop overinsertion and subsequent multimerization

21 January 2018

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Structural basis of latency in plasminogen activator inhibitor-1

21 January 2018

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Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 Asn-->Asp)

21 January 2018

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Development of a novel recombinant serpin with potential antithrombotic properties

21 January 2018

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[37] Reaction of protein sulfhydryl groups with Ellman's reagent.

21 January 2018

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Conformation of the reactive site loop of alpha 1-proteinase inhibitor probed by limited proteolysis

21 January 2018

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The contribution of the conserved hinge region residues of alpha1-antitrypsin to its reaction with elastase

21 January 2018

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Partial purification by guanosine-5'-diphosphate--agarose affinity chromatography of the 32,000 molecular weight polypeptide from mitochondria of brown adipose tissue

21 January 2018

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Mechanism of serpin action: evidence that C1 inhibitor functions as a suicide substrate

21 January 2018

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On the size of the active site in proteases. I. Papain

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.7.3905

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9020092%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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