Substrate-assisted catalysis of the PAR1 thrombin receptor. Enhancement of macromolecular association and cleavage (Q73004111)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11005807%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Substrate-assisted catalysis of the PAR1 thrombin receptor. Enhancement of macromolecular association and cleavage (English)

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31 October 2019

author name string

Jacques SL

1

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31 October 2019

LeMasurier M

2

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31 October 2019

Sheridan PJ

3

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31 October 2019

Seeley SK

4

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31 October 2019

Kuliopulos A

5

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31 October 2019

language of work or name

English

0 references

publication date

1 December 2000

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Journal of Biological Chemistry

31 October 2019

number of pages

8

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based on heuristic

inferred from page(s)

published in

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31 October 2019

volume

275

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31 October 2019

issue

52

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31 October 2019

page(s)

40671-40678

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Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

31 October 2019

cites work

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Cloning and characterization of human protease-activated receptor 4

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A dual thrombin receptor system for platelet activation

21 January 2018

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Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

21 January 2018

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Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets

21 January 2018

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Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

21 January 2018

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Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2

21 January 2018

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Mechanisms of thrombin receptor agonist specificity. Chimeric receptors and complementary mutations identify an agonist recognition site

21 January 2018

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Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes

21 January 2018

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Domains specifying thrombin–receptor interaction

21 January 2018

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Determinants of thrombin receptor cleavage. Receptor domains involved, specificity, and role of the P3 aspartate

21 January 2018

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Inhibitory mechanism of serpins. Interaction of thrombin with antithrombin and protease nexin 1

21 January 2018

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Thermodynamic investigation of hirudin binding to the slow and fast forms of thrombin: evidence for folding transitions in the inhibitor and protease coupled to binding

21 January 2018

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PAR3 is a cofactor for PAR4 activation by thrombin

21 January 2018

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Kinetic and ultraviolet spectroscopic studies of active-site mutants of delta 5-3-ketosteroid isomerase

21 January 2018

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Plasmin Desensitization of the PAR1 Thrombin Receptor: Kinetics, Sites of Truncation, and Implications for Thrombolytic Therapy†

21 January 2018

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Combined effects of two mutations of catalytic residues on the ketosteroid isomerase reaction

21 January 2018

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Thrombin adsorption to surfaces and prevention with polyethylene glycol 6,000.

21 January 2018

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Reaction of thrombins with human antithrombin III. I. Enzyme activity losses unrelated to the inhibitory reaction and their prevention

21 January 2018

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Cleavage of the thrombin receptor: identification of potential activators and inactivators

21 January 2018

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Binding of a thrombin receptor tethered ligand analogue to human platelet thrombin receptor

21 January 2018

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Proteolysis of the human platelet and endothelial cell thrombin receptor by neutrophil-derived cathepsin G.

21 January 2018

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Kinetic mechanism for the interaction of Hirulog with thrombin.

21 January 2018

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Effect of temperature on the association step in thrombin-fibrinogen interaction

21 January 2018

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The platelet high affinity binding site for thrombin mimics hirudin, modulates thrombin-induced platelet activation, and is distinct from the glycoprotein Ib-IX-V complex

21 January 2018

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Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M004544200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11005807%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference