Effect of quinidine on the interconversion kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6 (Q72897734)

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scientific article published on 01 January 1993

Language	Label	Description	Also known as
English	Effect of quinidine on the interconversion kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6	scientific article published on 01 January 1993

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scholarly article

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30 October 2019

Effect of quinidine on the interconversion kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6 (English)

1 reference

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30 October 2019

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D Young

1

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30 October 2019

K K Midha

2

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30 October 2019

M J Fossler

3

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30 October 2019

E M Hawes

4

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30 October 2019

J W Hubbard

5

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30 October 2019

G McKay

6

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30 October 2019

E D Korchinski

7

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publication date

1 January 1993

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30 October 2019

European Journal of Clinical Pharmacology

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44

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5

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433-438

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30 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00315539

0 references

Intersubject variation in the pharmacokinetics of haloperidol and reduced haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

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Oxidation of reduced haloperidol to haloperidol: involvement of human P450IID6 (sparteine/debrisoquine monooxygenase).

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

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Quinidine but not quinine inhibits in man the oxidative metabolic routes of methoxyphenamine which involve debrisoquine 4-hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

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HALOPERIDOL METABOLISM AND ANTIPSYCHOTIC EFFECT IN SCHIZOPHRENIA

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

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Use of antisera in the isolation of human specific conjugates of haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversions between haloperidol and reduced haloperidol in schizophrenic patients and guinea pigs: a steady-state study

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol and reduced haloperidol plasma levels in selected schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

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Isolation and Identification of a Metabolite of Haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

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Interactions in the renal and biliary elimination of digoxin: stereoselective difference between quinine and quinidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol reduction can be assayed in human red blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced haloperidol: Effects on striatal dopamine metabolism and conversion to haloperidol in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of quinidine on plasma concentrations of digoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinidine-digoxin interaction: Pharmacokinetics, underlying mechanism and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol reductase in human and guinea pig livers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol disposition is dependent on the debrisoquine hydroxylation phenotype: increased plasma levels of the reduced metabolite in poor metabolizers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Debrisoquine oxidation phenotype during neuroleptic monotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversion between haloperidol and reduced haloperidol in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

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Quinidine and the identification of drugs whose elimination is impaired in subjects classified as poor metabolizers of debrisoquine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The determination of essential clearance, volume, and residence time parameters of recirculating metabolic systems: the reversible metabolism of methylprednisolone and methylprednisone in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversion between haloperidol and reduced haloperidol in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An ultrasensitive method for the measurement of haloperidol and reduced haloperidol in plasma by high-performance liquid chromatography with coulometric detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00315539

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8359179%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8359179%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

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