A gut-homing, oligoclonal CD4+ T cell population in severe-combined immunodeficient mice expressing a rearranged, transgenic class I-restricted alpha beta T cell receptor (Q71889571)

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scientific article published on 01 June 1995

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English	A gut-homing, oligoclonal CD4+ T cell population in severe-combined immunodeficient mice expressing a rearranged, transgenic class I-restricted alpha beta T cell receptor	scientific article published on 01 June 1995

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scholarly article

1 reference

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22 October 2019

A gut-homing, oligoclonal CD4+ T cell population in severe-combined immunodeficient mice expressing a rearranged, transgenic class I-restricted alpha beta T cell receptor (English)

1 reference

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22 October 2019

author name string

Reimann J

1

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22 October 2019

Rudolphi A

2

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22 October 2019

Spiess S

3

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22 October 2019

Claesson MH

4

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22 October 2019

publication date

1 June 1995

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22 October 2019

European Journal of Immunology

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22 October 2019

25

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22 October 2019

6

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22 October 2019

1643-1653

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22 October 2019

Thymic selection: a matter of life and death

1 reference

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Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

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CD4+8- help prevents rapid deletion of CD8+ cells after a transient response to antigen

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The life span of naive alpha/beta T cells in secondary lymphoid organs

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Selection of intraepithelial lymphocytes with CD8 alpha/alpha co-receptors by self-antigen in the murine gut

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Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system

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The SCID mouse mutant: definition, characterization, and potential uses

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Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

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Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

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7 January 2021

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Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

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7 January 2021

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In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes.

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The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens

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Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules

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Immunohistology of T cell differentiation in the thymus of H-Y-specific T cell receptor alpha/beta transgenic mice

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An unusual lineage of alpha/beta T cells that contains autoreactive cells

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7 January 2021

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Regulation of T cell production in T cell receptor transgenic mice.

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Evidence of functional lymphocytes in some (leaky) scid mice

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Detection and characterization of functional T cells in mice with severe combined immune deficiency

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7 January 2021

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The immunoglobulin allotype contributed by peritoneal cavity B cells dominates in SCID mice reconstituted with allotype-disparate mixtures of splenic and peritoneal cavity B cells

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CD3+ T-cells in severe combined immunodeficiency (scid) mice III. Transferred congenic, selfreactive CD4+T cell clones rescue IgM-producing, Scid-derived B cells

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7 January 2021

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Adoptive transfer of neonatal T lymphocytes rescues immunoglobulin production in mice with severe combined immune deficiency

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7 January 2021

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CD3+ T cells in severe combined immune deficiency (scid) mice. I. Transferred purified CD4+ T cells, but not CD8+ T cells are engrafted in the spleen of congenic scid mice

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7 January 2021

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B cell function in SCID mice reconstituted with allotype-disparate spleen and peritoneal cavity B cells

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7 January 2021

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The diversity of in-frame TCR delta chain transcripts in aging SCID mice

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7 January 2021

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T cell memory is short-lived in the absence of antigen

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Selective engraftment of memory CD4+ T cells with an unusual recirculation pattern and a diverse T cell receptor-V beta repertoire into scid mice.

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Reconstitution of SCID mice with low numbers of CD4+ TCR alpha beta + T cells

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Gut-homing CD4+ T cell receptor alpha beta+ T cells in the pathogenesis of murine inflammatory bowel disease

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Inflammatory bowel disease (1)

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Physiological and molecular mechanisms of lymphocyte homing

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Activation of lamina propria T cells induces crypt epithelial proliferation and goblet cell depletion in cultured human fetal colon

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CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

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Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.

1 reference

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7 January 2021

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Identifiers

10.1002/EJI.1830250626

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7614993%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7614993%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

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