Neuronal protective and rescue effects of deprenyl against MPP+ dopaminergic toxicity (Q71370061)

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18 October 2019

title

Neuronal protective and rescue effects of deprenyl against MPP+ dopaminergic toxicity (English)

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18 October 2019

1

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18 October 2019

author name string

D L Murphy

series ordinal

2

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18 October 2019

C C Chiueh

series ordinal

3

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18 October 2019

publication date

1 January 1995

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18 October 2019

volume

100

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18 October 2019

page(s)

53-61

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18 October 2019

issue

1

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Oxygen free radicals and Parkinson's disease

18 October 2019

cites work

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12 December 2020

Oxidative stress as a cause of Parkinson's disease

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12 December 2020

Iron-melanin interaction and lipid peroxidation: implications for Parkinson's disease.

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12 December 2020

Does selegiline monotherapy in Parkinson's disease act by symptomatic or protective mechanisms?

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12 December 2020

Protective effect of deprenyl against 1-methyl-4-phenylpyridinium neurotoxicity in rat striatum.

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12 December 2020

Deprenyl protects dopamine neurons from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion.

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12 December 2020

Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease

1 reference

12 December 2020

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.

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12 December 2020

Selegiline can mediate neuronal rescue rather than neuronal protection

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12 December 2020

Apparent antioxidant effect of l-deprenyl on hydroxyl radical formation and nigral injury elicited by MPP+ in vivo

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12 December 2020

The effect of deprenyl (selegiline) on the natural history of Parkinson's disease

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12 December 2020

The molecular pharmacology of L-deprenyl

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12 December 2020

Dopamine in the extrapyramidal motor function. A study based upon the MPTP-induced primate model of parkinsonism.

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12 December 2020

The antiparkinson efficacy of deprenyl derives from transient improvement that is likely to be symptomatic

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12 December 2020

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

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12 December 2020

Effect of deprenyl on the progression of disability in early Parkinson's disease

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12 December 2020

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigra

1 reference

12 December 2020

The oxidant stress hypothesis in Parkinson's disease: evidence supporting it

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12 December 2020

Dopamine turnover and glutathione oxidation: implications for Parkinson disease

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12 December 2020

Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism.

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12 December 2020

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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12 December 2020

(−)Deprenyl and (−)parafluorodeprenyl-treatment prevents age-related pigment changes in the substantia nigra. A TV-image analysis of neuromelanin

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12 December 2020

Suppression of hydroxyl radical formation by MAO inhibitors: a novel possible neuroprotective mechanism in dopaminergic neurotoxicity.

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12 December 2020

An introduction to the free radical hypothesis in Parkinson's disease

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12 December 2020

Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+

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12 December 2020

(-)deprenyl increases activities of superoxide dismutase and catalase in certain brain regions in old male mice.

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12 December 2020

Deprenyl increases survival of rat foetal nigral neurones in culture

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12 December 2020

Rescue of dying neurons: A new action for deprenyl in MPTP parkinsonism

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12 December 2020

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12 December 2020

Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: effects of MPP+

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12 December 2020

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

1 reference

12 December 2020

Biochemical mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. Could oxidative stress be involved in the brain?

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12 December 2020

Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study

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12 December 2020

Deprenyl suppresses the oxidant stress associated with increased dopamine turnover

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12 December 2020

Enhanced hydroxyl radical generation by 2'-methyl analog of MPTP: suppression by clorgyline and deprenyl

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12 December 2020

Identifiers

DOI

10.1007/BF01276865

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18 October 2019

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