Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis (Q71046937)

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15 October 2019

title

Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis (English)

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15 October 2019

2

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15 October 2019

author name string

S Aoufouchi

series ordinal

1

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15 October 2019

C Milstein

series ordinal

3

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15 October 2019

language of work or name

English

0 references

publication date

1 May 1996

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15 October 2019

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15 October 2019

volume

85

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15 October 2019

page(s)

415-422

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15 October 2019

issue

3

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Nonsense codons within the Rous sarcoma virus gag gene decrease the stability of unspliced viral RNA

15 October 2019

cites work

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7 January 2021

Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability

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7 January 2021

Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping

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7 January 2021

Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA.

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7 January 2021

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.

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7 January 2021

A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro

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7 January 2021

Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA.

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7 January 2021

Regulated activity of the IgH intron enhancer (E mu) in the T lymphocyte lineage.

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7 January 2021

Maintenance of an open reading frame as an additional level of scrutiny during splice site selection

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7 January 2021

Pathways for the nuclear transport of proteins and RNAs

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Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

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7 January 2021

Rapid and efficient site-specific mutagenesis without phenotypic selection

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7 January 2021

The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon

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7 January 2021

Affinity maturation leads to differential expression of multiple copies of a κ light-chain transgene

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7 January 2021

Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing.

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7 January 2021

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase

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7 January 2021

Site-directed mutagenesis of adeno-associated virus type 2 structural protein initiation codons: effects on regulation of synthesis and biological activity

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7 January 2021

Nonsense mutations inhibit splicing of MVM RNA in cis when they interrupt the reading frame of either exon of the final spliced product.

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7 January 2021

mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor

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7 January 2021

mRNA surveillance by the Caenorhabditis elegans smg genes

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7 January 2021

T cell receptor-beta mRNA splicing: regulation of unusual splicing intermediates

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7 January 2021

A role for exon sequences and splice-site proximity in splice-site selection

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7 January 2021

The human immunodeficiency virus long terminal repeat includes a specialised initiator element which is required for Tat-responsive transcription

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7 January 2021

Exon definition may facilitate splice site selection in RNAs with multiple exons

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7 January 2021

Split genes and RNA splicing

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7 January 2021

Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.

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7 January 2021

Frameshift mutations in the v-src gene of avian sarcoma virus act in cis to specifically reduce v-src mRNA levels

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7 January 2021

SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex

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7 January 2021

Positive control of pre-mRNA splicing in vitro

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7 January 2021

Nonsense mutations in the dihydrofolate reductase gene affect RNA processing

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7 January 2021

10.1016/S0092-8674(00)81119-8

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8616896%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

1 reference