The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzyme (Q69057245)

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29 September 2019

title

The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzyme (English)

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29 September 2019

5

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author name string

Stammers DK

1

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29 September 2019

Champness JN

2

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29 September 2019

Beddell CR

3

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29 September 2019

Dann JG

4

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29 September 2019

Geddes AJ

6

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Ogg D

7

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North AC

8

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29 September 2019

language of work or name

English

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publication date

1 June 1987

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29 September 2019

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29 September 2019

volume

218

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issue

1

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29 September 2019

page(s)

178-184

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Inhibition of dihydrofolate reductase: effect of reduced nicotinamide adenine dinucleotide phosphate on the selectivity and affinity of diaminobenzylpyrimidines

29 September 2019

cites work

1 reference

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Dihydrofolate reductases as targets for inhibitors

21 January 2018

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The binding of trimethoprim to bacterial dihydrofolate reductase

21 January 2018

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Crystallographic investigation of the cooperative interaction between trimethoprim, reduced cofactor and dihydrofolate reductase.

21 January 2018

1 reference

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Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67.

21 January 2018

1 reference

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Trimethoprim binding to bacterial and mammalian dihydrofolate reductase: a comparison by proton and carbon-13 nuclear magnetic resonance

21 January 2018

1 reference

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A graphics model building and refinement system for macromolecules

21 January 2018

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Syntheses of alpha- and gamma-substituted amides, peptides, and esters of methotrexate and their evaluation as inhibitors of folate metabolism

21 January 2018

1 reference

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The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase

21 January 2018

1 reference

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Studies of amino-acid sequence in dihydrofolate reductase from a human methotrexate-resistant cell line KB/6b. Structural and kinetic comparison with mouse L1210 enzyme.

21 January 2018

1 reference

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10.1016/0014-5793(87)81042-6

21 January 2018

Identifiers

DOI

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29 September 2019

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