Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity (Q68579765)

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25 September 2019

title

Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity (English)

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25 September 2019

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L L Tsang

1

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25 September 2019

P B Farmer

series ordinal

2

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25 September 2019

A Gescher

series ordinal

3

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25 September 2019

J A Slack

series ordinal

4

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25 September 2019

publication date

1 January 1990

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Cancer Chemotherapy and Pharmacology

25 September 2019

published in

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25 September 2019

volume

26

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25 September 2019

issue

6

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25 September 2019

page(s)

429-436

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https://scigraph.springernature.com/pub.10.1007/bf02994094

25 September 2019

exact match

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cites work

Anti-tumour imidazotetrazines. Part XXI. Mitozolomide and temozolomide: probes for the major groove of DNA.

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12 December 2020

High-performance liquid chromatographic method with fluorescence detection for the simultaneous determination of metopimazine and its acid metabolite in serum

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The generation of potentially toxic, reactive iminium ions from the oxidative metabolism of xenobiotic N-alkyl compounds

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Antitumor imidazotetrazines. 20. Preparation of the 8-acid derivative of mitozolomide and its utility in the preparation of active antitumor agents

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Solid phase extraction chromatography and NMR spectroscopy (SPEC-NMR) for the rapid identification of drug metabolites in urine.

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12 December 2020

Identification by nuclear magnetic resonance and mass spectrometry of a glucuronic acid conjugate of o-hydroxybenzoic acid in normal urine and uremic plasma.

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12 December 2020

Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine

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12 December 2020

Structure determination of metabolites of rilmazafone, a1H-1,2,4-triazolyl benzophenone derivative in monkey urine

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12 December 2020

High-performance liquid chromatographic separation, isolation and identification of 1,2,3-thiadiazole-5-carboxaldoxime glucuronide in rabbit urine

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12 December 2020

A compound from uremic plasma and from normal urine isolated by liquid chromatography and identified by nuclear magnetic resonance

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12 December 2020

Antitumour imidazotetrazines. VII. Quantitative analysis of mitozolomide in biological fluids by high-performance liquid chromatography

1 reference

12 December 2020

Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent

1 reference

12 December 2020

Effects of N-methylformamide on the growth, cell cycle, and glutathione status of murine TLX5 lymphoma cells

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12 December 2020

Identifiers

DOI

10.1007/BF02994094

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2225314%20AND%20SRC:MED&resulttype=core&format=json

25 September 2019

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