The aprt heterozygote/hemizygote system for screening mutagenic agents allows detection of large deletions (Q68333283)

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23 September 2019

title

The aprt heterozygote/hemizygote system for screening mutagenic agents allows detection of large deletions (English)

1 reference

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chromosomal deletion syndrome

23 September 2019

main subject

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1 January 2023

mutagenicity tests

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1 January 2023

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

1 January 2023

author name string

W. E. Bradley

1

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1 January 2023

A. Belouchi

2

1 reference

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1 January 2023

K. Messing

3

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1 January 2023

language of work or name

English

0 references

publication date

1 May 1988

1 reference

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full work available at URL

23 September 2019

https://api.elsevier.com/content/article/PII:0027510788902382?httpAccept=text/xml

1 reference

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https://api.elsevier.com/content/article/PII:0027510788902382?httpAccept=text/plain

1 January 2023

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

1 January 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3362154%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

volume

199

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23 September 2019

page(s)

131-138

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23 September 2019

issue

1

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Conditional instability of induced variants of CHO. Transient sensitivity to contact with wild-type cells.

23 September 2019

cites work

2

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

High-frequency nonrandom mutational event at the adenine phosphoribosyltransferase (aprt) locus of sib-selected CHO variants heterozygous for aprt.

1 January 2023

3

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Changing mutant frequencies in cell populations subjected to long-term fractionated doses of radiation may reflect selection for radioresistance.

1 January 2023

4

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Molecular characterization of 15 rearrangements among 90 human in vivo somatic mutants shows that deletions predominate

1 January 2023

5

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Mutation and inactivation of mammalian cells by various ionising radiations

1 January 2023

6

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Resistance of cultured human fibroblasts and other cells to purine and pyrimidine analogues in relation to mutagenesis detection

1 January 2023

7

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Characterization of the biochemical basis of a complete deficiency of the adenine phosphoribosyl transferase (APRT)

1 January 2023

8

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Locus specificity in the mutability of L5178Y mouse lymphoma cells: the role of multilocus lesions

1 January 2023

9

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1 January 2023

10

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Deletion and amplification of the HGPRT locus in Chinese hamster cells

1 January 2023

11

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Chromosome 11 aberrations in small colony L5178Y TK-/- mutants early in their clonal history

1 January 2023

13

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Parameters governing the transfer of the genes for thymidine kinase and dihydrofolate reductase into mouse cells using metaphase chromosomes or DNA

1 January 2023

14

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Isolation of transforming DNA: cloning the hamster aprt gene

1 January 2023

15

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): utilization with a variety of mutagenic agents

1 January 2023

17

1 reference

https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Model involving gene inactivation in the generation of autosomal recessive mutants in mammalian cells in culture

1 January 2023

18

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Mechanism of mutation at the aprt locus in Chinese hamster ovary cells: analysis of heterozygotes and hemizygotes

1 January 2023

19

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1 January 2023

20

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Detection of deletion mutations in pSV2gpt-transformed cells

1 January 2023

22

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

Mutations induced by X-rays at the HPRT locus in cultured Chinese hamster cells are mostly large deletions

1 January 2023

23

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https://api.crossref.org/works/10.1016/0027-5107(88)90238-2

1 January 2023

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3362154%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

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