Effects of the prolyl 4-hydroxylase proinhibitor HOE 077 on human and rat hepatocytes in primary culture (Q68280179)

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23 September 2019

title

Effects of the prolyl 4-hydroxylase proinhibitor HOE 077 on human and rat hepatocytes in primary culture (English)

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23 September 2019

B. Clément

1

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24 October 2022

C. Chesné

2

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24 October 2022

A. P. Satie

3

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24 October 2022

A. Guillouzo

4

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24 October 2022

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1667668

24 October 2022

publication date

1 January 1991

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full work available at URL

23 September 2019

https://api.elsevier.com/content/article/PII:016882789190007X?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0168-8278(91)90007-X

https://api.elsevier.com/content/article/PII:016882789190007X?httpAccept=text/plain

24 October 2022

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24 October 2022

published in

Journal of Hepatology

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23 September 2019

volume

13 Suppl 3

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23 September 2019

page(s)

S41-7

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Structure of the extracellular matrix in normal and fibrotic liver: collagens and glycoproteins

23 September 2019

cites work

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MECHANISM OF COLLAGEN RESORPTION IN REVERSIBLE HEPATIC FIBROSIS

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Therapeutic strategies for hepatic fibrosis

24 October 2022

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A stereochemical concept for the catalytic mechanism of prolylhydroxylase: applicability to classification and design of inhibitors.

24 October 2022

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Prolyl 4-hydroxylase, a target enzyme for drug development. Design of suppressive agents and the in vitro effects of inhibitors and proinhibitors

24 October 2022

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Beneficial effects of inhibitors of prolyl 4-hydroxylase in CCl4-induced fibrosis of the liver in rats

24 October 2022

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Cellular origin of collagen and fibronectin in the liver

24 October 2022

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Cell types involved in collagen and fibronectin production in normal and fibrotic human liver

24 October 2022

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Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis.

24 October 2022

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Participation of hepatocytes in the production of basement membrane components in human and rat liver during the perinatal period

24 October 2022

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Differential expression of laminin chains and receptor (LBP-32) in fetal and neoplastic hepatocytes compared to normal adult hepatocytes in vivo and in culture

24 October 2022

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Expression of laminin and its receptor LBP-32 in human and rat hepatoma cells

24 October 2022

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Collagen formation by the hepatocyte in primary monolayer culture and in vivo

24 October 2022

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Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

24 October 2022

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Collagen production by rat hepatocytes and sinusoidal cells in primary monolayer culture

24 October 2022

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A procedure for light and electron microscopic intracellular immunolocalization of collagen and fibronectin in rat liver

24 October 2022

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Pharmacokinetics and metabolism of HOE 077. Preclinical studies

24 October 2022

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Pyridinedicarboxylates, the first mechanism-derived inhibitors for prolyl 4-hydroxylase, selectively suppress cellular hydroxyprolyl biosynthesis. Decrease in interstitial collagen and Clq secretion in cell culture

24 October 2022

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General pharmacology, toxicology and future clinical development of HOE 077

24 October 2022

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Ito-cell gene expression and collagen regulation

24 October 2022

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24 October 2022

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1667668%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

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