Gfra1 Underexpression Causes Hirschsprung's Disease and Associated Enterocolitis in Mice. (Q64914439)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

title

Gfra1 Underexpression Causes Hirschsprung's Disease and Associated Enterocolitis in Mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

main subject

Hirschsprung's disease

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Yulia Sidorova

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Maria Lindahl

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

author name string

L Lauriina Porokuokka

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Heikki T Virtanen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Tatiana Danilova

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Mart Saarma

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Jaan-Olle Andressoo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

publication date

27 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

Cellular and molecular gastroenterology and hepatology

16 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

page(s)

655-678

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

16 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6444303/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Hirschsprung's disease: associated abnormalities and demography

1 reference

12 December 2020

Origin, course, and endings of abnormal enteric nerve fibres in Hirschsprung's disease defined by whole-mount immunohistochemistry.

1 reference

12 December 2020

The pathophysiology of Hirschsprung's-associated enterocolitis: importance of histologic correlates

1 reference

12 December 2020

Origin and morphology of nerve fibers in the aganglionic colon of the lethal spotted (ls/ls) mutant mouse

1 reference

12 December 2020

Nitric oxide synthase is deficient in the aganglionic colon of patients with Hirschsprung's disease.

1 reference

12 December 2020

Nitric oxide synthase distribution in the enteric nervous system of Hirschsprung's disease

1 reference

12 December 2020

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

1 reference

12 December 2020

Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts.

1 reference

12 December 2020

Defects in enteric innervation and kidney development in mice lacking GDNF

1 reference

12 December 2020

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

1 reference

12 December 2020

Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.

1 reference

12 December 2020

GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney

1 reference

12 December 2020

GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys.

1 reference

12 December 2020

A single rostrocaudal colonization of the rodent intestine by enteric neuron precursors is revealed by the expression of Phox2b, Ret, and p75 and by explants grown under the kidney capsule or in organ culture

1 reference

12 December 2020

Developmental regulation of GDNF response and receptor expression in the enteric nervous system

1 reference

12 December 2020

A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells.

1 reference

12 December 2020

Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis

1 reference

12 December 2020

The GDNF family: signalling, biological functions and therapeutic value

1 reference

12 December 2020

Glial cell line-derived neurotrophic factor family receptors are abnormally expressed in aganglionic bowel of a subpopulation of patients with Hirschsprung's disease

1 reference

12 December 2020

GDNF availability determines enteric neuron number by controlling precursor proliferation.

1 reference

12 December 2020

Congenital megacolon; a comparison of the spastic and hypertrophied segments with respect to Cholinesterase activities and sensitivities to Acetylcholine, DFP and the barium ion

1 reference

12 December 2020

Cholinesterases and monoamine oxidase in congenital megacolon

1 reference

12 December 2020

Transgenic mice with a hypomorphic NADPH-cytochrome P450 reductase gene: effects on development, reproduction, and microsomal cytochrome P450

1 reference

12 December 2020

Identifying candidate Hirschsprung disease-associated RET variants

1 reference

12 December 2020

New insights into the pathogenesis of Hirschsprung's associated enterocolitis

1 reference

12 December 2020

Current concepts in RET-related genetics, signaling and therapeutics

1 reference

12 December 2020

GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion

1 reference

12 December 2020

Conditional ablation of GFRalpha1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype.

1 reference

12 December 2020

Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies

1 reference

12 December 2020

Hirschsprung disease, associated syndromes and genetics: a review

1 reference

12 December 2020

Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice.

1 reference

12 December 2020

Practical pathology and genetics of Hirschsprung's disease

1 reference

12 December 2020

Murine model of Hirschsprung-associated enterocolitis. I: phenotypic characterization with development of a histopathologic grading system

1 reference

12 December 2020

Persephin signaling through GFRalpha1: the potential for the treatment of Parkinson's disease

1 reference

12 December 2020

Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a resultant mouse model with global suppression of P450 reductase expression

1 reference

12 December 2020

Hirschsprung's disease.

1 reference

12 December 2020

Generation of a Slc39a8 hypomorph mouse: markedly decreased ZIP8 Zn²⁺/(HCO₃⁻)₂ transporter expression

1 reference

12 December 2020

Copy number variants in candidate genes are genetic modifiers of Hirschsprung disease

1 reference

12 December 2020

Genetic interactions and modifier genes in Hirschsprung's disease

1 reference

12 December 2020

The enteric nervous system

1 reference

12 December 2020

Hirschsprung-associated enterocolitis: prevention and therapy

1 reference

12 December 2020

Building a brain in the gut: development of the enteric nervous system

1 reference

12 December 2020

The developmental etiology and pathogenesis of Hirschsprung disease.

1 reference

12 December 2020

Hirschsprung-associated enterocolitis: pathogenesis, treatment and prevention

1 reference

12 December 2020

GDNF signaling levels control migration and neuronal differentiation of enteric ganglion precursors.

1 reference

12 December 2020

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system

1 reference

12 December 2020

Altered goblet cell differentiation and surface mucus properties in Hirschsprung disease

1 reference

12 December 2020

Altered goblet cell function in Hirschsprung's disease.

1 reference

12 December 2020

10.1016/J.JCMGH.2018.12.007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30594740%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

1 reference