Potent systemic anticancer activity of adenovirally expressed EGFR-selective TRAIL fusion protein (Q64376217)

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14 January 2020

title

Potent systemic anticancer activity of adenovirally expressed EGFR-selective TRAIL fusion protein (English)

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14 January 2020

1

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14 January 2020

Hidde J. Haisma

8

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14 January 2020

author name string

Gooitzen M van Dam

2

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14 January 2020

Marco de Bruyn

3

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14 January 2020

Manon van Riezen

4

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14 January 2020

Marike Dijkstra

5

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Gera Kamps

6

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14 January 2020

Wijnand Helfrich

7

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language of work or name

English

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publication date

23 September 2008

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14 January 2020

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14 January 2020

volume

16

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issue

12

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page(s)

1919-1926

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Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer.

14 January 2020

cites work

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7 January 2021

Transductional targeting of adenovirus vectors for gene therapy

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7 January 2021

Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter

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7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

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7 January 2021

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

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7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

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7 January 2021

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

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7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

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7 January 2021

Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor

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7 January 2021

The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation

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7 January 2021

Differential activation of TRAIL-R1 and -2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative

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7 January 2021

Targeted induction of apoptosis for cancer therapy: current progress and prospects.

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7 January 2021

Target cell-restricted apoptosis induction of acute leukemic T cells by a recombinant tumor necrosis factor-related apoptosis-inducing ligand fusion protein with specificity for human CD7.

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7 January 2021

Simultaneous inhibition of epidermal growth factor receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv:sTRAIL fusion protein with speci

1 reference

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7 January 2021

Exceptionally potent anti-tumor bystander activity of an scFv:sTRAIL fusion protein with specificity for EGP2 toward target antigen-negative tumor cells

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7 January 2021

Target cell-restricted and -enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma-associated antigen EGP2.

1 reference

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7 January 2021

Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein

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7 January 2021

Liver failure caused by herpes simplex virus thymidine kinase plus ganciclovir therapy is associated with mitochondrial dysfunction and mitochondrial DNA depletion

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7 January 2021

Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene

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7 January 2021

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

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7 January 2021

Targeting of adenoviral vectors through a bispecific single-chain antibody

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7 January 2021

Tumorigenesis and the angiogenic switch

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7 January 2021

Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors

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7 January 2021

The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.203

7 January 2021

Valproic acid enhances gene expression from viral gene transfer vectors

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https://api.crossref.org/works/10.1038%2FMT.2008.203

7 January 2021

A simplified system for generating recombinant adenoviruses

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https://api.crossref.org/works/10.1038%2FMT.2008.203

7 January 2021

CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors

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7 January 2021

Identifiers

DOI

10.1038/MT.2008.203

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18813279%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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