Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus (Q64119844)

15

Antonio Lanzavecchia

0 references

David Veesler

18

David Veesler

0 references

Michela Perotti

4

Michela Perotti

0 references

Jessica Marcandalli

1

Jessica Marcandalli

0 references

author name string

Brooke Fiala

2

0 references

Sebastian Ols

3

0 references

Willem de van der Schueren

5

0 references

Joost Snijder

6

0 references

Edgar Hodge

7

0 references

Mark Benhaim

8

0 references

Rashmi Ravichandran

9

0 references

Lauren Carter

10

0 references

Will Sheffler

11

0 references

Livia Brunner

12

0 references

Maria Lawrenz

13

0 references

Patrice Dubois

14

0 references

Kelly K Lee

17

0 references

Colin E Correnti

19

0 references

Lance J Stewart

20

0 references

David Baker

21

0 references

Karin Loré

22

0 references

Laurent Perez

23

0 references

Neil P King

Risk of primary infection and reinfection with respiratory syncytial virus

24

0 references

language of work or name

English

0 references

publication date

7 March 2019

0 references

published in

Cell

0 references

volume

176

0 references

issue

6

0 references

page(s)

1420-1431.e17

0 references

cites work

1 reference

12 December 2020

Relationship of serum antibody to risk of respiratory syncytial virus infection in elderly adults

1 reference

12 December 2020

Correlates of immunity to respiratory syncytial virus (RSV) associated-hospitalization: establishment of minimum protective threshold levels of serum neutralizing antibodies

1 reference

12 December 2020

Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy

1 reference

12 December 2020

Automated molecular microscopy: the new Leginon system

1 reference

12 December 2020

EMAN2: an extensible image processing suite for electron microscopy

1 reference

12 December 2020

Semi-automated data processing of hydrogen exchange mass spectra using HX-Express

1 reference

12 December 2020

The burden of respiratory syncytial virus infection in young children

1 reference

12 December 2020

DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

1 reference

12 December 2020

Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming

1 reference

12 December 2020

Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns

1 reference

12 December 2020

Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial.

1 reference

12 December 2020

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

1 reference

12 December 2020

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

1 reference

12 December 2020

Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors

1 reference

12 December 2020

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction

1 reference

12 December 2020

Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention

1 reference

12 December 2020

Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults

1 reference

12 December 2020

Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy

1 reference

12 December 2020

Technology transfer of an oil-in-water vaccine-adjuvant for strengthening pandemic influenza preparedness in Indonesia

1 reference

12 December 2020

Respiratory syncytial virus fusion glycoprotein expressed in insect cells form protein nanoparticles that induce protective immunity in cotton rats

1 reference

12 December 2020

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

1 reference

12 December 2020

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

1 reference

12 December 2020

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

1 reference

12 December 2020

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

1 reference

12 December 2020

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

1 reference

12 December 2020

Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra

1 reference

12 December 2020

Engineering synthetic vaccines using cues from natural immunity

1 reference

12 December 2020

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

1 reference

12 December 2020

Respiratory syncytial virus: virology, reverse genetics, and pathogenesis of disease

1 reference

12 December 2020

Accurate design of co-assembling multi-component protein nanomaterials

1 reference

12 December 2020

T follicular helper cell differentiation, function, and roles in disease

1 reference

12 December 2020

1 reference

12 December 2020

HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.

1 reference

12 December 2020

Synthetic Nanoparticles for Vaccines and Immunotherapy

1 reference

12 December 2020

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

1 reference

12 December 2020

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

1 reference

12 December 2020

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

1 reference

12 December 2020

Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity

1 reference

12 December 2020

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

1 reference

12 December 2020

Gctf: Real-time CTF determination and correction

1 reference

12 December 2020

Self-assembling protein nanoparticles in the design of vaccines

1 reference

12 December 2020

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.

1 reference

12 December 2020

Influence of Respiratory Syncytial Virus F Glycoprotein Conformation on Induction of Protective Immune Responses.

1 reference

12 December 2020

Engineering virus-like particles as vaccine platforms

1 reference

12 December 2020

Vaccines against respiratory syncytial virus: The time has finally come

1 reference

12 December 2020

Taxonomy of the order Mononegavirales: update 2016

1 reference

12 December 2020

Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

1 reference

12 December 2020

Accurate design of megadalton-scale two-component icosahedral protein complexes

1 reference

12 December 2020

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

1 reference

12 December 2020

Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates

1 reference

12 December 2020

The coming of age of de novo protein design

1 reference

12 December 2020

A Randomized, Controlled, Observer-Blinded Phase 1 Study of the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine With or Without Alum Adjuvant

1 reference

12 December 2020

Corrigendum: Design of a hyperstable 60-subunit protein icosahedron.

1 reference

12 December 2020

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2.

1 reference

12 December 2020

Immunological Principles Guiding the Rational Design of Particles for Vaccine Delivery

1 reference

12 December 2020

Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors

1 reference

12 December 2020

Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus

1 reference

12 December 2020

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

1 reference

12 December 2020

Vitrification after multiple rounds of sample application and blotting improves particle density on cryo-electron microscopy grids

1 reference

12 December 2020

Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine

1 reference

12 December 2020

A Phase 2 randomized, observer-blind, placebo-controlled, dose-ranging trial of aluminum-adjuvanted respiratory syncytial virus F particle vaccine formulations in healthy women of childbearing age.

1 reference

12 December 2020

UCSF ChimeraX: Meeting Modern Challenges in Visualization and Analysis.

1 reference

12 December 2020

Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV.

1 reference

12 December 2020

Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

1 reference

12 December 2020

Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model.

1 reference

12 December 2020

Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies

1 reference

12 December 2020