The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans (Q64063954)

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30 April 2020

title

The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans (English)

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30 April 2020

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30 April 2020

author name string

Pui Wang

1

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30 April 2020

Wenjun Song

2

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30 April 2020

Bobo Wing-Yee Mok

3

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30 April 2020

Min Zheng

4

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30 April 2020

Siu-Ying Lau

5

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30 April 2020

Siwen Liu

6

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30 April 2020

Pin Chen

7

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30 April 2020

Xiaofeng Huang

8

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30 April 2020

Honglian Liu

9

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30 April 2020

Conor J Cremin

10

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language of work or name

English

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publication date

22 March 2019

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volume

11

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issue

3

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Creative Commons Attribution 4.0 International

30 April 2020

page(s)

292

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copyright license

start time

22 March 2019

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase.

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Nuclear factor 90 negatively regulates influenza virus replication by interacting with viral nucleoprotein

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Dating the emergence of pandemic influenza viruses

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Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host

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12 December 2020

Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in mice

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12 December 2020

The PB2-E627K mutation attenuates viruses containing the 2009 H1N1 influenza pandemic polymerase

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12 December 2020

Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

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12 December 2020

Reversion of PB2-627E to -627K during replication of an H5N1 Clade 2.2 virus in mammalian hosts depends on the origin of the nucleoprotein

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Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells

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Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

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Human infection with a novel avian-origin influenza A (H7N9) virus

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The effect of the PB2 mutation 627K on highly pathogenic H5N1 avian influenza virus is dependent on the virus lineage.

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PB2 mutations D701N and S714R promote adaptation of an influenza H5N1 virus to a mammalian host

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Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7.

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Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.

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Influenza A(H5N8) Virus Similar to Strain in Korea Causing Highly Pathogenic Avian Influenza in Germany

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Full-Genome Sequence of Influenza A(H5N8) Virus in Poultry Linked to Sequences of Strains from Asia, the Netherlands, 2014

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An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells.

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12 December 2020

Identifiers

DOI

10.3390/V11030292

1 reference

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