Concentration and avidity of antibodies to different circumsporozoite epitopes correlate with RTS,S/AS01E malaria vaccine efficacy (Q64054854)

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26 April 2020

title

Concentration and avidity of antibodies to different circumsporozoite epitopes correlate with RTS,S/AS01E malaria vaccine efficacy (English)

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26 April 2020

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26 April 2020

David Kwame Dosoo

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26 April 2020

Itziar Ubillos

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Ruth Aguilar

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Ousmane Traore

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Chenjerai Jairoce

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Selidji Todagbe Agnandji

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Benjamin Mordmüller

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Halidou Tinto

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Joseph J Campo

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Gemma Moncunill Piñas

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Claudia Daubenberger

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Simon Kariuki

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26 April 2020

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Ben Gyan

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Clarissa Valim

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26 April 2020

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Kwaku Poku Asante

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26 April 2020

author name string

Hèctor Sanz

2

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26 April 2020

Hermann Sorgho

3

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26 April 2020

Maximilian Mpina

5

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26 April 2020

Tom Ford

8

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26 April 2020

Núria Díez-Padrisa

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Nana Aba Williams

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26 April 2020

Aintzane Ayestaran

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26 April 2020

Augusto J Nhabomba

13

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John Waitumbi

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26 April 2020

Seth Owusu-Agyei

22

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Salim Abdulla

18

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26 April 2020

John J Aponte

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26 April 2020

Dobaño, C.

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Sanz, H.

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Sorgho, H.

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Dosoo, D.

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Mpina, M.

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Ubillos, I.

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Aguilar, R.

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Ford, T.

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Díez-Padrisa, N.

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Williams, N.A.

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Ayestaran, A.et.al.

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language of work or name

English

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publication date

15 May 2019

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26 April 2020

2019

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published in

Nature Communications

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26 April 2020

volume

10

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26 April 2020

issue

1

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26 April 2020

page(s)

2174

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First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

26 April 2020

cites work

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7 January 2021

Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites

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7 January 2021

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

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Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children

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Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

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Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

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RTS,S: Toward a first landmark on the Malaria Vaccine Technology Roadmap

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7 January 2021

Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

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7 January 2021

Insights into long-lasting protection induced by RTS,S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican children

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7 January 2021

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

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7 January 2021

Duration of vaccine efficacy against malaria: 5th year of follow-up in children vaccinated with RTS,S/AS02 in Mozambique

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7 January 2021

Four-year efficacy of RTS,S/AS01E and its interaction with malaria exposure

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7 January 2021

The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity

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7 January 2021

Unexpected fold in the circumsporozoite protein target of malaria vaccines

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7 January 2021

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

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7 January 2021

A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease

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7 January 2021

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7 January 2021

Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults

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7 January 2021

C3d binding to the circumsporozoite protein carboxy-terminus deviates immunity against malaria.

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7 January 2021

The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites

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7 January 2021

Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in African children

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7 January 2021

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7 January 2021

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7 January 2021

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A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/31092823

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41467-019-10195-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31092823%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

0 references

1 reference

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26 April 2020

PubMed publication ID

31092823

1 reference