Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology (Q63345230)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

Myeloid differentiation primary response gene 88

5 April 2020

main subject

pathology

0 references

1 reference

GOA release 2020-03-11

Toll-like receptor 2

1 reference

GOA release 2020-03-11

Toll-like receptor 4

1 reference

GOA release 2020-03-11

author

Grant T Corbett

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

9

Elliott J Mufson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

12

David A Bennett

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

author name string

Suresh B Rangasamy

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Malabendu Jana

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Avik Roy

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Madhuchhanda Kundu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Sujyoti Chandra

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Susanta Mondal

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Sridevi Dasarathi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Rama K Mishra

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Chi-Hao Luan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Kalipada Pahan

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

language of work or name

English

0 references

publication date

10 July 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

5 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

volume

128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

page(s)

4297-4312

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6159992/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Neuropathological stageing of Alzheimer-related changes

1 reference

12 December 2020

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

12 December 2020

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

12 December 2020

Correlation of astrocytic S100 beta expression with dystrophic neurites in amyloid plaques of Alzheimer's disease.

1 reference

12 December 2020

Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory.

1 reference

12 December 2020

Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau.

1 reference

12 December 2020

Microglia as mediators of inflammatory and degenerative diseases

1 reference

12 December 2020

Tau is essential to beta -amyloid-induced neurotoxicity

1 reference

12 December 2020

Individual differences in rates of change in cognitive abilities of older persons.

1 reference

12 December 2020

Inferences, questions and possibilities in Toll-like receptor signalling

1 reference

12 December 2020

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

1 reference

12 December 2020

Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions.

1 reference

12 December 2020

Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

1 reference

12 December 2020

Comparison of penetratin and other homeodomain-derived cell-penetrating peptides: interaction in a membrane-mimicking environment and cellular uptake efficiency

1 reference

12 December 2020

Regulation of inducible nitric oxide synthase gene in glial cells.

1 reference

12 December 2020

Neuropathology of older persons without cognitive impairment from two community-based studies

1 reference

12 December 2020

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

1 reference

12 December 2020

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

1 reference

12 December 2020

Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

1 reference

12 December 2020

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

1 reference

12 December 2020

Protective effects of NSAIDs on the development of Alzheimer disease

1 reference

12 December 2020

Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease

1 reference

12 December 2020

Campylobacter jejuni drives MyD88-independent interleukin-6 secretion via Toll-like receptor 2.

1 reference

12 December 2020

Regulation of innate immune responses in the brain

1 reference

12 December 2020

CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.

1 reference

12 December 2020

Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease

1 reference

12 December 2020

Deletion of CD14 attenuates Alzheimer's disease pathology by influencing the brain's inflammatory milieu

1 reference

12 December 2020

Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons

1 reference

12 December 2020

Clostridium butyricum activates TLR2-mediated MyD88-independent signaling pathway in HT-29 cells

1 reference

12 December 2020

Toll-like receptor 2 -196 to -174 del polymorphism influences the susceptibility of Han Chinese people to Alzheimer's disease

1 reference

12 December 2020

Increased expressions of TLR2 and TLR4 on peripheral blood mononuclear cells from patients with Alzheimer's disease

1 reference

12 December 2020

TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation

1 reference

12 December 2020

Effective pharmacological management of Alzheimer's disease.

1 reference

12 December 2020

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

1 reference

12 December 2020

Overview and findings from the religious orders study

1 reference

12 December 2020

The Role of TLR2 in Infection and Immunity

1 reference

12 December 2020

Testing NF-κB-based therapy in hemiparkinsonian monkeys

1 reference

12 December 2020

Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense

1 reference

12 December 2020

Protection of Tregs, suppression of Th1 and Th17 cells, and amelioration of experimental allergic encephalomyelitis by a physically-modified saline

1 reference

12 December 2020

Up-regulation of neurotrophic factors by cinnamon and its metabolite sodium benzoate: therapeutic implications for neurodegenerative disorders.

1 reference

12 December 2020

The history of Toll-like receptors - redefining innate immunity.

1 reference

12 December 2020

Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α.

1 reference

12 December 2020

Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome

1 reference

12 December 2020

Protection of dopaminergic neurons in a mouse model of Parkinson's disease by a physically-modified saline containing charge-stabilized nanobubbles.

1 reference

12 December 2020

TLR2 and TLR4 in autoimmune diseases: a comprehensive review

1 reference

12 December 2020

Exercise, APOE genotype, and the evolution of the human lifespan

1 reference

12 December 2020

Assembly and localization of Toll-like receptor signalling complexes.

1 reference

12 December 2020

Hyperphosphorylation of Tau at Ser396 occurs in the much earlier stage than appearance of learning and memory disorders in 5XFAD mice.

1 reference

12 December 2020

Cinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: implications for multiple sclerosis therapy

1 reference

12 December 2020

Tau phosphorylation at serine 396 residue is required for hippocampal LTD

1 reference

12 December 2020

Immune attack: the role of inflammation in Alzheimer disease.

1 reference

12 December 2020

Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP

1 reference

12 December 2020

HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice.

1 reference

12 December 2020

Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease

1 reference

12 December 2020

Structural Elucidation of the Cell-Penetrating Penetratin Peptide in Model Membranes at the Atomic Level: Probing Hydrophobic Interactions in the Blood-Brain Barrier

1 reference

12 December 2020

Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid β-Protein Oligomers

1 reference

12 December 2020

Identification and characterization of PPARα ligands in the hippocampus

1 reference

12 December 2020

Cell Penetrating Peptides as Molecular Carriers for Anti-Cancer Agents.

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI96209

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29990310%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference