Exploiting CRISPR-Cas9 technology to investigate individual histone modifications (Q61489847)

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31 March 2020

title

Exploiting CRISPR-Cas9 technology to investigate individual histone modifications (English)

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31 March 2020

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5 February 2019

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6 February 2019

Suppressor of clathrin deficiency 6, putative

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6 February 2019

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3

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31 March 2020

Tim Nicolai Siegel

series ordinal

4

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31 March 2020

author name string

Juan-José Vasquez

series ordinal

1

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31 March 2020

Carolin Wedel

series ordinal

2

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31 March 2020

language of work or name

English

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publication date

1 October 2018

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31 March 2020

published in

Nucleic Acids Research

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31 March 2020

volume

46

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31 March 2020

issue

18

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31 March 2020

page(s)

e106

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Creative Commons Attribution-NonCommercial 4.0 International

31 March 2020

copyright license

start time

15 June 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Double-stranded RNA induces mRNA degradation in Trypanosoma brucei

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Genomic maps and comparative analysis of histone modifications in human and mouse

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Tagging a T. brucei RRNA locus improves stable transfection efficiency and circumvents inducible expression position effects

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Unusual histone modifications in Trypanosoma brucei

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Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids

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Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei.

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Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169

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Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei

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Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei

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Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters.

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The role of the 5'-3' exoribonuclease XRNA in transcriptome-wide mRNA degradation

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Trypanosomal histone γH2A and the DNA damage response

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Multiplex genome engineering using CRISPR/Cas systems

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RNA-guided human genome engineering via Cas9

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A histone mutant reproduces the phenotype caused by loss of histone-modifying factor Polycomb.

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Chromatin remodeling at DNA double-strand breaks

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DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes

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Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages.

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Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels

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Genome engineering using CRISPR-Cas9 system.

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Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells.

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CRISPR-Cas9-mediated single-gene and gene family disruption in Trypanosoma cruzi

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A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids.

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12 December 2020

First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites.

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Flexible guide-RNA design for CRISPR applications using Protospacer Workbench.

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12 December 2020

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12 December 2020

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Codon choice directs constitutive mRNA levels in trypanosomes.

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Codon usage bias controls mRNA and protein abundance in trypanosomatids.

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKY517

1 reference

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31 March 2020

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31 March 2020

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