IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral Infections (Q61450240)

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20 April 2020

title

IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral Infections (English)

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4

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3

Cheryl A Winkler

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20 April 2020

author name string

Xuesen Zhao

series ordinal

1

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20 April 2020

Jiarui Li

series ordinal

2

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20 April 2020

Ju-Tao Guo

series ordinal

5

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20 April 2020

language of work or name

English

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publication date

1 January 2018

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Frontiers in Microbiology

20 April 2020

published in

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20 April 2020

volume

9

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20 April 2020

page(s)

3228

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Creative Commons Attribution 4.0 International

20 April 2020

copyright license

start time

8 January 2019

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus

1 reference

12 December 2020

Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections

1 reference

12 December 2020

Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3

1 reference

12 December 2020

Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms

1 reference

12 December 2020

The small interferon-induced transmembrane genes and proteins

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12 December 2020

The IFITM proteins inhibit HIV-1 infection

1 reference

12 December 2020

Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus

1 reference

12 December 2020

IFITM3 restricts the morbidity and mortality associated with influenza

1 reference

12 December 2020

Interferon-inducible transmembrane proteins of the innate immune response act as membrane organizers by influencing clathrin and v-ATPase localization and function

1 reference

12 December 2020

S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus

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12 December 2020

Ifitm3 limits the severity of acute influenza in mice

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12 December 2020

IFITM1 is a tight junction protein that inhibits hepatitis C virus entry

1 reference

12 December 2020

The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization

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12 December 2020

Evolutionary dynamics of the interferon-induced transmembrane gene family in vertebrates

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12 December 2020

Enhanced survival of lung tissue-resident memory CD8⁺ T cells during infection with influenza virus due to selective expression of IFITM3.

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12 December 2020

IFITM proteins restrict viral membrane hemifusion

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12 December 2020

Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals

1 reference

12 December 2020

The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry

1 reference

12 December 2020

Interferon-inducible transmembrane protein 3 (IFITM3) restricts reovirus cell entry

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12 December 2020

The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication

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12 December 2020

IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus

1 reference

12 December 2020

Palmitoylation on conserved and nonconserved cysteines of murine IFITM1 regulates its stability and anti-influenza A virus activity.

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12 December 2020

A functional promoter polymorphism of IFITM3 is associated with susceptibility to pediatric tuberculosis in Han Chinese population

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12 December 2020

IFITM3 and susceptibility to respiratory viral infections in the community

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12 December 2020

Interferon-induced transmembrane protein 3 is a type II transmembrane protein

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12 December 2020

IFITMs restrict the replication of multiple pathogenic viruses

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12 December 2020

Negative regulation of interferon-induced transmembrane protein 3 by SET7-mediated lysine monomethylation

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12 December 2020

Amphotericin B increases influenza A virus infection by preventing IFITM3-mediated restriction

1 reference

12 December 2020

Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model

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12 December 2020

Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection

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12 December 2020

Identification of an endocytic signal essential for the antiviral action of IFITM3.

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12 December 2020

Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination

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12 December 2020

IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion

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12 December 2020

Interferon induction of IFITM proteins promotes infection by human coronavirus OC43

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12 December 2020

Influenza A virus-induced degradation of eukaryotic translation initiation factor 4B contributes to viral replication by suppressing IFITM3 protein expression.

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12 December 2020

Swine interferon-induced transmembrane protein, sIFITM3, inhibits foot-and-mouth disease virus infection in vitro and in vivo

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12 December 2020

IFITM proteins inhibit entry driven by the MERS-coronavirus spike protein: evidence for cholesterol-independent mechanisms

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12 December 2020

IFITM3 polymorphism rs12252-C restricts influenza A viruses

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12 December 2020

Regulation of the trafficking and antiviral activity of IFITM3 by post-translational modifications.

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12 December 2020

IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity

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12 December 2020

IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread.

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12 December 2020

A sorting signal suppresses IFITM1 restriction of viral entry

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12 December 2020

Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment

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12 December 2020

IFITM-Family Proteins: The Cell's First Line of Antiviral Defense

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12 December 2020

Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort

1 reference

12 December 2020

Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses

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12 December 2020

E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3

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12 December 2020

IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein.

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12 December 2020

Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8+ T Cell Priming

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12 December 2020

The IFITMs Inhibit Zika Virus Replication

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12 December 2020

The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis

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12 December 2020

The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses

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12 December 2020

IFITM3 and severe influenza virus infection. No evidence of genetic association

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12 December 2020

Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity.

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12 December 2020

Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction.

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12 December 2020

Identification of Interferon-Stimulated Gene Proteins That Inhibit Human Parainfluenza Virus Type 3

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12 December 2020

Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFNγ- and TNFα-Mediated Antiproliferative Effects and Necroptosis

1 reference

12 December 2020

Interferon-Induced Transmembrane Protein 3 Inhibits Hantaan Virus Infection, and Its Single Nucleotide Polymorphism rs12252 Influences the Severity of Hemorrhagic Fever with Renal Syndrome

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12 December 2020

The V3 Loop of HIV-1 Env Determines Viral Susceptibility to IFITM3 Impairment of Viral Infectivity

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12 December 2020

The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis

1 reference

12 December 2020

ZMPSTE24 defends against influenza and other pathogenic viruses

1 reference

12 December 2020

pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs

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12 December 2020

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection

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12 December 2020

Δ20 IFITM2 differentially restricts X4 and R5 HIV-1.

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12 December 2020

IFITM3 Rs12252-C Variant Increases Potential Risk for Severe Influenza Virus Infection in Chinese Population

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12 December 2020

SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans

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12 December 2020

IFITM3 requires an amphipathic helix for antiviral activity.

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12 December 2020

Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs

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12 December 2020

The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity.

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12 December 2020

Lack of Truncated IFITM3 Transcripts in Cells Homozygous for the rs12252-C Variant That is Associated With Severe Influenza Infection

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12 December 2020

Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses

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12 December 2020

Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation.

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12 December 2020

The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.

1 reference

12 December 2020

Influenza A Virus Facilitates Its Infectivity by Activating p53 to Inhibit the Expression of Interferon-Induced Transmembrane Proteins.

1 reference

12 December 2020

Association between IFITM3 rs12252 polymorphism and influenza susceptibility and severity: A meta-analysis

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12 December 2020

mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3

1 reference

12 December 2020

Functional mapping of regions involved in the negative imprinting of virion particles infectivity and in target cell protection by the Interferon-Induced Transmembrane Protein 3 (IFITM3) against HIV-1

1 reference

12 December 2020

Identifiers

DOI

10.3389/FMICB.2018.03228

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20 April 2020

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20 April 2020

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