Raf-1 Is Involved in the Regulation of the Interaction between Guanine Nucleotide Exchange Factor and Ha-Ras (Q61136597)

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scientific article published in Journal of Biological Chemistry

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English	Raf-1 Is Involved in the Regulation of the Interaction between Guanine Nucleotide Exchange Factor and Ha-Ras	scientific article published in Journal of Biological Chemistry

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7 December 2019

Raf-1 is involved in the regulation of the interaction between guanine nucleotide exchange factor and Ha-ras. Evidences for a function of Raf-1 and phosphatidylinositol 3-kinase upstream to Ras (English)

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Europe PubMed Central

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7 December 2019

Carmela Giglione

1

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7 December 2019

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A Parmeggiani

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7 December 2019

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1 December 1998

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7 December 2019

Journal of Biological Chemistry

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7 December 2019

273

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7 December 2019

52

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7 December 2019

34737-34744

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7 December 2019

How Ras-related proteins talk to their effectors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

A novel family of Ras-binding domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Protein modules and signalling networks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Proteins regulating Ras and its relatives

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Ras interaction with the GTPase-activating protein (GAP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Enhancement of the GDP-GTP exchange of RAS proteins by the carboxyl-terminal domain of SCD25.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Characterization of mammalian C-CDC25Mm exchange factor and kinetic properties of the exchange reaction intermediate p21.C-CDC25Mm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Properties of the catalytic domain of sdc25p, a yeast GDP/GTP exchange factor of Ras proteins. Complexation with wild-type Ras2p, [S24N]Ras2p and [R80D, N81D]Ras2p

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

ralGDS family members interact with the effector loop of ras p21.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

A New Function of p120-GTPase-activating Protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Direct measurement of the binding of RAS to neurofibromin using a scintillation proximity assay

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Equilibrium and kinetic measurements reveal rapidly reversible binding of Ras to Raf.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

The N-terminal moiety of CDC25(Mm), a GDP/GTP exchange factor of Ras proteins, controls the activity of the catalytic domain. Modulation by calmodulin and calpain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Two distinct Raf domains mediate interaction with Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Stimulation of p21 ras upon T-cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Mechanism of inhibition by arachidonic acid of the catalytic activity of Ras GTPase-activating proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Ras-GTPase activating protein (GAP): a putative effector for Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Mechanisms regulating Raf-1 activity in signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Regulation of interaction of ras p21 with RalGDS and Raf-1 by cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Ras/Rap effector specificity determined by charge reversal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Differential structural requirements for interaction of Ras protein with its distinct downstream effectors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Distal switch II region of Ras2p is required for interaction with guanine nucleotide exchange factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

The structural basis of the activation of Ras by Sos

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.52.34737

21 January 2018

Identifiers

10.1074/JBC.273.52.34737

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856997%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856997%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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