Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations (Q60951067)

4

0 references

Mihai Netea

3

object named as

Mihai G Netea

0 references

author name string

Silvia Sánchez-Ramón

1

0 references

Óscar Palomares

5

0 references

José Luis Subiza

Creative Commons Attribution 4.0 International

6

0 references

language of work or name

English

0 references

publication date

17 December 2018

3 references

15 December 2019

29 April 2020

2 October 2020

2018

0 references

published in

Frontiers in Immunology

2 references

15 December 2019

2 October 2020

9

0 references

page(s)

2936

0 references

copyright license

3 references

Europe PubMed Central

15 December 2019

Europe PubMed Central

29 April 2020

Europe PubMed Central

Evidence for macrophage-mediated protection against lethal Candida albicans infection.

2 October 2020

cites work

1 reference

12 December 2020

Effects of muramyl dipeptide treatment on resistance to infection with Toxoplasma gondii in mice

1 reference

12 December 2020

Effects of an immunostimulating agent on acute exacerbations and hospitalizations in patients with chronic obstructive pulmonary disease. The PARI-IS Study Steering Committee and Research Group. Prevention of Acute Respiratory Infection by an Immuno

1 reference

12 December 2020

Innovations and strategies for the development of anticancer vaccines

1 reference

12 December 2020

Safety and efficacy of two courses of OM-85 BV in the prevention of respiratory tract infections in children during 12 months

1 reference

12 December 2020

Influence of Mycobacterium bovis Bacillus Calmette-Guerin on Antibody and Cytokine Responses to Human Neonatal Vaccination

1 reference

12 December 2020

Fungal β-Glucans and Mammalian Immunity

1 reference

12 December 2020

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

1 reference

12 December 2020

Taking advantage of the positive side-effects of smallpox vaccination

1 reference

12 December 2020

Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus

1 reference

12 December 2020

Lung infection--a public health priority

1 reference

12 December 2020

Vaccinia scars associated with better survival for adults. An observational study from Guinea-Bissau

1 reference

12 December 2020

An hypothesis to link the opposing immunological effects induced by the bacterial lysate OM-89 in urinary tract infection and rheumatoid arthritis

1 reference

12 December 2020

Bacterial extract (OM-89) specific and non specific immunomodulation in rheumatoid arthritis patients.

1 reference

12 December 2020

Vaccinia scars associated with improved survival among adults in rural Guinea-Bissau

1 reference

12 December 2020

The perfect mix: recent progress in adjuvant research

1 reference

12 December 2020

Trivalent live attenuated intranasal influenza vaccine administered during the 2003-2004 influenza type A (H3N2) outbreak provided immediate, direct, and indirect protection in children

1 reference

12 December 2020

Clonal dissection of the human memory B-cell repertoire following infection and vaccination

1 reference

12 December 2020

Prophylactic administration of bacterially derived immunomodulators improves the outcome of influenza virus infection in a murine model

1 reference

12 December 2020

The bacterial extract OM-85 BV protects mice against influenza and Salmonella infection.

1 reference

12 December 2020

Mucosal administration of flagellin protects mice from Streptococcus pneumoniae lung infection

1 reference

12 December 2020

The immunostimulant OM-85 BV prevents wheezing attacks in preschool children

1 reference

12 December 2020

Efficacy of whole-cell killed bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic

1 reference

12 December 2020

CpG oligodeoxynucleotides protect against the 2009 H1N1 pandemic influenza virus infection in a murine model

1 reference

12 December 2020

The epidemiology of urinary tract infection

1 reference

12 December 2020

Sublingual therapeutic immunization with a polyvalent bacterial preparation in patients with recurrent respiratory infections: immunomodulatory effect on antigen-specific memory CD4+ T cells and impact on clinical outcome.

1 reference

12 December 2020

Trained immunity: a memory for innate host defense

1 reference

12 December 2020

Randomized trial of BCG vaccination at birth to low-birth-weight children: beneficial nonspecific effects in the neonatal period?

1 reference

12 December 2020

Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes

1 reference

12 December 2020

FimH, a TLR4 ligand, induces innate antiviral responses in the lung leading to protection against lethal influenza infection in mice.

1 reference

12 December 2020

Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection

1 reference

12 December 2020

Louis pasteur, the father of immunology?

1 reference

12 December 2020

1 reference

12 December 2020

Evaluation of a therapeutic vaccine for the prevention of recurrent urinary tract infections versus prophylactic treatment with antibiotics

1 reference

12 December 2020

Epidemic pertussis in 2012--the resurgence of a vaccine-preventable disease

1 reference

12 December 2020

Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes.

1 reference

12 December 2020

Detection of functional antigen-specific T cells from urine of non-muscle invasive bladder cancer patients.

1 reference

12 December 2020

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

1 reference

12 December 2020

Bacillus Calmette-Guerin (BCG) immunotherapy for bladder cancer: current understanding and perspectives on engineered BCG vaccine

1 reference

12 December 2020

Dectin-1 plays a redundant role in the immunomodulatory activities of β-glucan-rich ligands in vivo.

1 reference

12 December 2020

A small jab - a big effect: nonspecific immunomodulation by vaccines

1 reference

12 December 2020

Antibiotics for treatment and prevention of exacerbations of chronic obstructive pulmonary disease

1 reference

12 December 2020

Acute sinusitis in children: do antibiotics have any role?

1 reference

12 December 2020

Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity

1 reference

12 December 2020

Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection

1 reference

12 December 2020

Innate immune memory: towards a better understanding of host defense mechanisms

1 reference

12 December 2020

Immunological memory within the innate immune system

1 reference

12 December 2020

Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations

1 reference

12 December 2020

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

1 reference

12 December 2020

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity.

1 reference

12 December 2020

The effects of orally administered Beta-glucan on innate immune responses in humans, a randomized open-label intervention pilot-study

1 reference

12 December 2020

Extending the clinical horizons of mucosal bacterial vaccines: current evidence and future prospects

1 reference

12 December 2020

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer

1 reference

12 December 2020

Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18

1 reference

12 December 2020

Enhanced Mucosal Antibody Production and Protection against Respiratory Infections Following an Orally Administered Bacterial Extract

1 reference

12 December 2020

Comparison of sublingual therapeutic vaccine with antibiotics for the prophylaxis of recurrent urinary tract infections

1 reference

12 December 2020

Trained innate immunity as underlying mechanism for the long-term, nonspecific effects of vaccines

1 reference

12 December 2020

Infection in an aging population.

1 reference

12 December 2020

Immunological memory: lessons from the past and a look to the future

1 reference

12 December 2020

Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host with Saccharomyces cerevisiae.

1 reference

12 December 2020

Innate immune memory: Implications for host responses to damage-associated molecular patterns

1 reference

12 December 2020

Trained immunity: A program of innate immune memory in health and disease.

1 reference

12 December 2020

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

1 reference

12 December 2020

TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection

1 reference

12 December 2020

Harnessing the beneficial heterologous effects of vaccination

1 reference

12 December 2020

Clash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses

1 reference

12 December 2020

Unravelling the nature of non-specific effects of vaccines-A challenge for innate immunologists

1 reference

12 December 2020

Nonspecific effect of BCG vaccination at birth on early childhood infections: a randomized, clinical multicenter trial

1 reference

12 December 2020

New Biological Insights in the Immunomodulatory Effects of Mucosal Polybacterial Vaccines in Clinical Practice.

1 reference

12 December 2020

β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

1 reference

12 December 2020

Immunometabolic Pathways in BCG-Induced Trained Immunity

1 reference

12 December 2020

MV140, a sublingual polyvalent bacterial preparation to treat recurrent urinary tract infections, licenses human dendritic cells for generating Th1, Th17, and IL-10 responses via Syk and MyD88.

1 reference

12 December 2020

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

1 reference

12 December 2020

Preconditioning with Lipopolysaccharide or Lipoteichoic Acid Protects against Staphylococcus aureus Mammary Infection in Mice.

1 reference

12 December 2020

Human dendritic cells activated with MV130 induce Th1, Th17 and IL-10 responses via RIPK2 and MyD88 signalling pathways

1 reference

12 December 2020

Blood monocytes sample MelanA/MART1 antigen for long-lasting cross-presentation to CD8+ T cells after differentiation into dendritic cells

1 reference

12 December 2020

Effects of Bacillus Calmette-Guérin (BCG) vaccination at birth on T and B lymphocyte subsets: Results from a clinical randomized trial

1 reference

12 December 2020

How inflammasomes inform adaptive immunity

1 reference

12 December 2020

Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.

1 reference

12 December 2020

In silico design of knowledge-based Plasmodium falciparum epitope ensemble vaccines

1 reference

12 December 2020

Pneumococcal whole-cell and protein-based vaccines: changing the paradigm

1 reference

12 December 2020

First experience in the UK of treating women with recurrent urinary tract infections with the bacterial vaccine Uromune®.

1 reference

12 December 2020

Broncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP.

1 reference

12 December 2020

The use of databases, data mining and immunoinformatics in vaccinology: where are we?

1 reference

12 December 2020

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

1 reference

12 December 2020

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.

1 reference

12 December 2020

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity.

1 reference

12 December 2020

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.

1 reference

12 December 2020

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis.

1 reference

12 December 2020

Trained Innate Immunity as a Novel Mechanism Linking Infection and the Development of Atherosclerosis.

1 reference

12 December 2020

Adjuvant Effect of Bacille Calmette-Guérin on Hepatitis B Vaccine Immunogenicity in the Preterm and Term Newborn.

1 reference

12 December 2020

Non-specific Effect of Vaccines: Immediate Protection against Respiratory Syncytial Virus Infection by a Live Attenuated Influenza Vaccine.

1 reference

12 December 2020

The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders.

1 reference

12 December 2020

Nonspecific immunomodulators for recurrent respiratory tract infections, wheezing and asthma in children: a systematic review of mechanistic and clinical evidence.

1 reference

12 December 2020

Novel Platforms for the Development of a Universal Influenza Vaccine.

1 reference

12 December 2020

Innate immune memory in the brain shapes neurological disease hallmarks

1 reference

12 December 2020

What if protective immunity is antigen-driven and not due to so-called "memory" B and T cells?

1 reference

12 December 2020

Innate immune memory: An evolutionary perspective.

1 reference

12 December 2020

Trained immunity as a novel therapeutic strategy.

1 reference

12 December 2020

The Elusive Anti-Candida Vaccine: Lessons From the Past and Opportunities for the Future.

1 reference

12 December 2020

Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice.

1 reference

12 December 2020

Non-specific effects of vaccines: Current evidence and potential implications

1 reference

12 December 2020

Induction of innate immune memory: the role of cellular metabolism

1 reference

12 December 2020

Mevalonate Metabolism in Cancer Stemness and Trained Immunity

1 reference

12 December 2020