Characterization of Mutations in NOT2 Indicates that it Plays an Important Role in Maintaining the Integrity of the CCR4–NOT Complex (Q60300131)

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12 November 2019

title

Characterization of mutations in NOT2 indicates that it plays an important role in maintaining the integrity of the CCR4-NOT complex (English)

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12 November 2019

1

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12 November 2019

author name string

John D Benson

series ordinal

2

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12 November 2019

Clyde L Denis

series ordinal

3

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12 November 2019

language of work or name

English

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publication date

1 September 2002

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Journal of Molecular Biology

12 November 2019

published in

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12 November 2019

volume

322

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12 November 2019

issue

1

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12 November 2019

page(s)

27-39

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The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively

12 November 2019

cites work

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A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling

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CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context

7 January 2021

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DBF2, a cell cycle-regulated protein kinase, is physically and functionally associated with the CCR4 transcriptional regulatory complex

7 January 2021

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Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex

7 January 2021

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Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes

7 January 2021

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Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme

7 January 2021

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The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

7 January 2021

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Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex

7 January 2021

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DBF2 protein kinase binds to and acts through the cell cycle-regulated MOB1 protein

7 January 2021

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CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase

7 January 2021

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The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

7 January 2021

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Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

7 January 2021

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The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

7 January 2021

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NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization

7 January 2021

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MOT2 encodes a negative regulator of gene expression that affects basal expression of pheromone-responsive genes in Saccharomyces cerevisiae

7 January 2021

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The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promoters

7 January 2021

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The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes

7 January 2021

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Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex

7 January 2021

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Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions

7 January 2021

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Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast

7 January 2021

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Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme

7 January 2021

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A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

7 January 2021

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ADR1 activation domains contact the histone acetyltransferase GCN5 and the core transcriptional factor TFIIB.

7 January 2021

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10.1016/S0022-2836(02)00707-6

7 January 2021

Identifiers

DOI

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12 November 2019

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