Demonstration of Epitope-Spreading Phenomena in Bullous Pemphigoid: Results of a Prospective Multicenter Study (Q60240341)

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title

Demonstration of epitope-spreading phenomena in bullous pemphigoid: results of a prospective multicenter study (English)

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1

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Jean-Philippe Lacour

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Francesco Sera

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Leena Bruckner-Tuderman

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Leena Bruckner-Tuderman

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author name string

Sybille Thoma-Uszynski

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Valentina Calabresi

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Lionel Fontao

4

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Silke C Hofmann

5

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Giovanna Zambruno

9

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Luca Borradori

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Michael Hertl

11

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language of work or name

English

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publication date

23 June 2011

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Journal of Investigative Dermatology

5 February 2020

published in

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volume

131

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issue

11

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page(s)

2271-2280

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https://scigraph.springernature.com/pub.10.1038/jid.2011.180

5 February 2020

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Role of the bullous pemphigoid antigen 180 (BP180) in the assembly of hemidesmosomes and cell adhesion--reexpression of BP180 in generalized atrophic benign epidermolysis bullosa keratinocytes.

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Epitope spreading: lessons from autoimmune skin diseases

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Usefulness of BP230 and BP180-NC16a enzyme-linked immunosorbent assays in the initial diagnosis of bullous pemphigoid: a retrospective study of 138 patients

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Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

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The intracellular and extracellular domains of BP180 antigen comprise novel epitopes targeted by pemphigoid gestationis autoantibodies

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Sequential intramolecular epitope spreading of humoral responses to human BPAG2 in a transgenic model

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Characterization of the anti-BP180 autoantibody reactivity profile and epitope mapping in bullous pemphigoid patients

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Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid

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Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180

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Comparative structural analysis of desmoplakin, bullous pemphigoid antigen and plectin: members of a new gene family involved in organization of intermediate filaments

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Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?

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Rabbits immunized with a peptide encoded for by the 230-kD bullous pemphigoid antigen cDNA develop an enhanced inflammatory response to UVB irradiation: a potential animal model for bullous pemphigoid

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Demonstration of the molecular shape of BP180, a 180-kDa bullous pemphigoid antigen and its potential for trimer formation

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7 January 2021

Severity and phenotype of bullous pemphigoid relate to autoantibody profile against the NH2- and COOH-terminal regions of the BP180 ectodomain

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Experimental bullous pemphigoid generated in mice with an antigenic epitope of the human hemidesmosomal protein BP230

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A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180.

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Development of a novel ELISA system for detection of anti-BP180 IgG and characterization of autoantibody profile in bullous pemphigoid patients

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B-cell epitope spreading is a critical step for the switch from C-protein-induced myocarditis to dilated cardiomyopathy

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Analysis of antigens targeted by circulating IgG and IgA autoantibodies in 50 patients with cicatricial pemphigoid

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Humanization of autoantigen

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IgG autoantibodies from bullous pemphigoid (BP) patients bind antigenic sites on both the extracellular and the intracellular domains of the BP antigen 180

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IgG autoantibodies from bullous pemphigoid patients recognize multiple antigenic reactive sites located predominantly within the B and C subdomains of the COOH-terminus of BP230

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