Diphtheria toxin receptor–mediated conditional and targeted cell ablation in transgenic mice (Q60017797)

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9 November 2019

title

Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice (English)

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9 November 2019

7

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9 November 2019

author name string

Saito M

1

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9 November 2019

Iwawaki T

2

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9 November 2019

Taya C

3

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9 November 2019

Yonekawa H

4

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9 November 2019

Noda M

5

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9 November 2019

Inui Y

6

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9 November 2019

Kimata Y

8

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9 November 2019

Tsuru A

9

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9 November 2019

Kohno K

10

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9 November 2019

publication date

1 August 2001

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9 November 2019

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9 November 2019

volume

19

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9 November 2019

page(s)

746-750

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9 November 2019

issue

8

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https://scigraph.springernature.com/pub.10.1038/90795

9 November 2019

exact match

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cites work

Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene

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7 January 2021

Genetic ablation: targeted expression of a toxin gene causes microphthalmia in transgenic mice.

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Dwarf mice produced by genetic ablation of growth hormone-expressing cells.

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Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene

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Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice

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Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity.

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Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

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One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell

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7 January 2021

Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta

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7 January 2021

Diphtheria toxin entry into cells is facilitated by low pH.

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7 January 2021

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement

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7 January 2021

Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins

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7 January 2021

Diphtheria toxin and related proteins: effect of route of injection on toxicity and the determination of cytotoxicity for various cultured cells

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Methylamine facilitates demonstration of specific uptake of diphtheria toxin by CHO cell and toxin-resistant CHO cell mutants

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Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor.

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Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity.

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Targeting of an inducible toxic phenotype in animal cells

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Immunotoxin-mediated conditional disruption of specific neurons in transgenic mice.

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Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination.

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Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function

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Conditional lineage ablation to model human diseases

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Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity

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An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice.

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Genetic alteration of catecholamine specificity in transgenic mice.

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Isolation of full-length putative rat lysophospholipase cDNA using improved methods for mRNA isolation and cDNA cloning

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Expression and activity-dependent changes of a novel limbic-serine protease gene in the hippocampus.

1 reference

7 January 2021

Identifiers

DOI

10.1038/90795

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9 November 2019

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