Role of neurokinin 1 receptors in dextran sulfate-induced colitis: studies with gene-deleted mice and the selective receptor antagonist netupitant (Q59852872)

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English	Role of neurokinin 1 receptors in dextran sulfate-induced colitis: studies with gene-deleted mice and the selective receptor antagonist netupitant	article

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scholarly article

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6 March 2020

Role of neurokinin 1 receptors in dextran sulfate-induced colitis: studies with gene-deleted mice and the selective receptor antagonist netupitant (English)

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6 March 2020

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ChEBI release 2020-05-28

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István Szitter

1

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Erika Pintér

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Anikó Perkecz

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József Kun

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László Kereskai

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Claudio Pietra

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Andreas Zimmer

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Alexandra Berger

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Zsuzsanna Helyes

12

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Agnes Kemény

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Christopher J Paige

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publication date

28 January 2014

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Inflammation Research

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63

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5

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399-409

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6 March 2020

https://scigraph.springernature.com/pub.10.1007/s00011-014-0712-x

0 references

Comparative effects of nonpeptide tachykinin receptor antagonists on experimental gut inflammation in rats and guinea-pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurokinin 1 receptor antagonists--current prospects

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of neuropeptides in inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substance P and vasoactive intestinal polypeptide but not calcitonin gene-related peptide concentrations are reduced in patients with moderate and severe ulcerative colitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proximodistal aggravation of colitis depends on substance P released from TRPV1-expressing sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell developmental blockage by tachykinin antagonists and the role of hemokinin 1 in T lymphopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An unidentified depressor substance in certain tissue extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of transient receptor potential vanilloid 1 (TRPV1) receptors in dextran sulfate-induced colitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substance K : A novel mammalian tachykinin that differs from substance P in its pharmacological profile

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection from DNBS-induced colitis by the tachykinin NK(1) receptor antagonist SR140333 in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tachykinin receptors and tachykinin receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rectal substance P concentrations are increased in ulcerative colitis but not in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible existence of a new tachykinin receptor subtype in the guinea pig ileum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of a functional cDNA for rat substance P receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotransmitter functions of mammalian tachykinins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered nociception, analgesia and aggression in mice lacking the receptor for substance P

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of tachykinin production in airway epithelia in response to viral infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New challenges in the study of the mammalian tachykinins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central effects of selective NK1 and NK3 tachykinin receptor agonists on two models of experimentally-induced colitis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulatory properties of substance P: the gastrointestinal system as a model

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of a rat neuromedin K receptor cDNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both neurokinin A and substance P bind to NK1 receptors in guinea-pig lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of the tachykinin NK2 receptor antagonist nepadutant in acute rectocolitis induced by diluted acetic acid in guinea-pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropeptide K: isolation, structure and biological activities of a novel brain tachykinin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in substance P precursor mRNA in noninflamed small-bowel sections in patients with Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo pharmacological characterization of the novel NK₁ receptor selective antagonist Netupitant

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tachykinin NK1 and NK2 receptor-mediated control of peristaltic propulsion in the guinea-pig small intestine in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Search for a physiological role of substance P in gastrointestinal motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dual nature of the tachykinin NK1 receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tachykinin NK(1)receptor-mediated inhibitory responses in the guinea-pig small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tachykinin receptors in the gut: physiological and pathological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of TNBS colitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemokinins and endokinins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tachykinin NK3 receptor antagonist, SR 142801 (osanetant), prevents substance P-induced bronchial hyperreactivity in guinea-pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cDNA cloning of bovine substance-K receptor through oocyte expression system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiinflammatory and analgesic effects of somatostatin released from capsaicin-sensitive sensory nerve terminals in a Freund's adjuvant-induced chronic arthritis model in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hapten-induced model of chronic inflammation and ulceration in the rat colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropeptide-gamma: a peptide isolated from rabbit intestine that is derived from gamma-preprotachykinin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in substance P-immunoreactive innervation of human colon associated with ulcerative colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00011-014-0712-X

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6 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24468892%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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