E-cadherin impairment increases cell survival through Notch-dependent upregulation of Bcl-2 (Q59182383)

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14 February 2020

title

E-cadherin impairment increases cell survival through Notch-dependent upregulation of Bcl-2 (English)

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14 February 2020

author

António Carlos Ferreira

1

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14 February 2020

Fatima Carneiro

6

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14 February 2020

Raquel Seruca

7

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14 February 2020

José C. Machado

8

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14 February 2020

author name string

Gianpaolo Suriano

2

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14 February 2020

Nuno Mendes

3

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14 February 2020

Bárbara Gomes

4

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14 February 2020

Xiaogang Wen

5

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publication date

11 October 2011

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14 February 2020

published in

Human Molecular Genetics

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14 February 2020

volume

21

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issue

2

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14 February 2020

page(s)

334-343

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Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

14 February 2020

cites work

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E-cadherin missense mutations, associated with hereditary diffuse gastric cancer (HDGC) syndrome, display distinct invasive behaviors and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia.

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Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression

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Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells.

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Notch, Myc and breast cancer

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Loss of functional E-cadherin renders cells more resistant to the apoptotic agent taxol in vitro

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21 January 2018

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Genetic screening for hereditary diffuse gastric cancer

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Aberrant activation of notch signaling in human breast cancer

21 January 2018

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Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin

21 January 2018

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Notch signaling mediates hypoxia-induced tumor cell migration and invasion

21 January 2018

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21 January 2018

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21 January 2018

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Relationship between E-cadherin gene mutation and p53 gene mutation, p53 accumulation, Bcl-2 expression and Ki-67 staining in diffuse-type gastric carcinoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDR469

1 reference

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14 February 2020

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