DNA damage sensor γ -H2AX is increased in preneoplastic lesions of hepatocellular carcinoma (Q59034315)

2

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Masayuki Kubota

3

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Mami Osawa

4

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Masaaki Takamura

5

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Satoshi Yamagiwa

6

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Yutaka Aoyagi

7

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Ayumi Sanpei

8

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Shun Fujimaki

The Scientific World Journal

9

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language of work or name

English

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publication date

2013

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published in

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volume

2013

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page(s)

597095

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copyright license

Creative Commons Attribution 3.0 Unported

start time

1 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes

30 November 2018

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Importance of DNA damage checkpoints in the pathogenesis of human cancers

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Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis

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Hepatic oxidative DNA damage is associated with increased risk for hepatocellular carcinoma in chronic hepatitis C.

30 November 2018

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Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation.

30 November 2018

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Hepatocellular carcinoma pathogenesis: from genes to environment

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Phosphorylated histone H2AX in relation to cell survival in tumor cells and xenografts exposed to single and fractionated doses of X-rays

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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Molecular mechanism of the recruitment of NBS1/hMRE11/hRAD50 complex to DNA double-strand breaks: NBS1 binds to gamma-H2AX through FHA/BRCT domain

30 November 2018

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Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells

30 November 2018

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Hepatitis B virus X protein inhibits nucleotide excision repair

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Hepatitis B x protein inhibits p53-dependent DNA repair in primary mouse hepatocytes

30 November 2018

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HBx gene of hepatitis B virus induces liver cancer in transgenic mice

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The increasing incidence of hepatocellular carcinoma

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inferred from PubMed ID database lookup

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Immunohistochemical study of the relationship between 8-hydroxy-2′-deoxyguanosine levels in noncancerous region and postoperative recurrence of hepatocellular carcinoma in remnant liver

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