TGFB induced factor homeobox 1 (Q5889831)

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mammalian protein found in Homo sapiens

• 5'-TG-3'-interacting factor 1
• transforming growth factor-beta-induced factor
• TGIF1
• homeobox protein TGIF1
• TALE homeobox TG-interacting factor

edit

Language	Label	Description	Also known as
English	TGFB induced factor homeobox 1	mammalian protein found in Homo sapiens	5'-TG-3'-interacting factor 1 transforming growth factor-beta-induced factor TGIF1 homeobox protein TGIF1 TALE homeobox TG-interacting factor

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q15583

part of

Homeobox-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15583

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox KN domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q15583

encoded by

TGIF1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q15583

molecular function

DNA binding

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q15583

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IEA

protein binding

determination method

IPI

5 references

retrieved

8 April 2019

stated in

Next-generation sequencing to generate interactome datasets

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IPI

retrieved

8 April 2019

stated in

Towards a proteome-scale map of the human protein–protein interaction network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IPI

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IPI

retrieved

8 April 2019

stated in

Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signalling

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IPI

retrieved

8 April 2019

stated in

TGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesis

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IPI

DNA-binding transcription factor activity

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

TAS

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IDA

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method

IDA

IMP

4 references

retrieved

5 June 2018

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15583&geneProductId=UniProtKB:Q15583

determination method

IMP

retrieved

5 June 2018

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15583&geneProductId=UniProtKB:Q15583

determination method

IDA

retrieved

8 April 2019

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IMP

retrieved

8 April 2019

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IDA

transcription corepressor activity

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

TAS

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

ISA

ISM

NAS

3 references

retrieved

8 April 2019

stated in

A census of human transcription factors: function, expression and evolution

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

NAS

retrieved

8 April 2019

stated in

A census of human transcription factors: function, expression and evolution

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

ISM

retrieved

8 April 2019

stated in

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

ISA

co-SMAD binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IEA

cell component

nucleus

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q15583

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IEA

nucleoplasm

determination method

IDA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IDA

biological process

regulation of transcription, DNA-templated

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IEA

negative regulation of gene expression

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IEA

multicellular organism development

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

TAS

cellular response to growth factor stimulus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IEA

negative regulation of transcription by RNA polymerase II

determination method

IDA

TAS

IMP

4 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

TAS

retrieved

8 April 2019

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

TAS

retrieved

8 April 2019

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IMP

retrieved

8 April 2019

stated in

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15583

determination method

IDA

transcription, DNA-templated

determination method

IEA

1 reference

retrieved

5 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q15583

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15583&geneProductId=UniProtKB:Q15583

determination method

IEA

Gene Atlas image

PBB GE TGIF1 203313 s at fs.png
732 × 530; 11 KB

0 references

has part(s)

Homeobox KN domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15583

Homeobox domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15583

Identifiers

RefSeq protein ID

NP_001265611

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_001265613

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_001265615

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_003235

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_733796

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_775299

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_775300

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_775301

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_775302

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_775303

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_777480

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

XP_016881447

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_001361325

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

NP_001361326

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7050

UniProt protein ID

Q15583

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q15583

Ensembl protein ID

ENSP00000327959

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000327959

ENSP00000339631

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000339631

ENSP00000343969

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000343969

ENSP00000383031

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000383031

ENSP00000384133

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000384133

ENSP00000384970

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000384970

ENSP00000385206

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000385206

ENSP00000447747

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000447747

ENSP00000449501

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449501

ENSP00000450025

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000450025

ENSP00000483499

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000483499

ENSP00000446838

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000446838

ENSP00000446944

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000446944

ENSP00000448121

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000448121

ENSP00000448934

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000448934

ENSP00000449287

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449287

ENSP00000449531

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449531

ENSP00000449580

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449580

ENSP00000449722

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449722

ENSP00000449973

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449973

ENSP00000462285

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000462285

PDB structure ID

2LK2

1 reference

stated in

UniProt

UniProt protein ID

Q15583

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q5889831&oldid=2022908548"