Epidermal growth factor receptor gene copy number may predict lapatinib sensitivity in HER2-positive metastatic breast cancer (Q58849503)

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25 February 2020

title

Epidermal growth factor receptor gene copy number may predict lapatinib sensitivity in HER2-positive metastatic breast cancer (English)

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25 February 2020

main subject

metastatic breast cancer

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10

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25 February 2020

Patrizia Vici

11

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25 February 2020

Mirella Marino

12

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25 February 2020

Stefania Gori

13

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25 February 2020

author name string

Roberta Merola

2

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25 February 2020

Gianluigi Ferretti

3

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25 February 2020

Anna Di Benedetto

4

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Barbara Antoniani

5

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Cristiana Ercolani

6

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Cecilia Nisticò

7

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Paola Papaldo

8

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Mariangela Ciccarese

9

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Claudio Botti

14

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Paola Malaguti

15

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Francesco Cognetti

16

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Marcella Mottolese

17

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Alessandra Fabi

1

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language of work or name

English

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publication date

9 March 2013

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Expert Opinion on Pharmacotherapy

25 February 2020

published in

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volume

14

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25 February 2020

page(s)

699-706

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25 February 2020

issue

6

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Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group

25 February 2020

cites work

1 reference

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Adjuvant/neoadjuvant trastuzumab therapy in women with HER-2/neu-overexpressing breast cancer: a systematic review

21 January 2018

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Lapatinib plus capecitabine for HER2-positive advanced breast cancer

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Efficacy and safety of lapatinib as first-line therapy for ErbB2-amplified locally advanced or metastatic breast cancer

21 January 2018

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Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL.

21 January 2018

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A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses

21 January 2018

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Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

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Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

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Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas

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Molecular analysis of metaplastic breast carcinoma: high EGFR copy number via aneusomy

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EGFR expression and gene copy number in triple-negative breast carcinoma.

21 January 2018

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Exon 8 amplification of epidermal growth factor receptor (EGFR) in invasive breast carcinomas.

21 January 2018

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Molecular predictors of response to trastuzumab and lapatinib in breast cancer.

21 January 2018

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

21 January 2018

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Correlation of HER2, p95HER2 and HER3 expression and treatment outcome of lapatinib plus capecitabine in her2-positive metastatic breast cancer

21 January 2018

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Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies

21 January 2018

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HER-2 gene amplification, HER-2 and epidermal growth factor receptor mRNA and protein expression, and lapatinib efficacy in women with metastatic breast cancer.

21 January 2018

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Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients

21 January 2018

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Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis.

21 January 2018

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PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients

21 January 2018

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EGFR gene copy number assessment from areas with highest EGFR expression predicts response to anti-EGFR therapy in colorectal cancer

21 January 2018

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Frequently increased epidermal growth factor receptor (EGFR) copy numbers and decreased BRCA1 mRNA expression in Japanese triple-negative breast cancers

21 January 2018

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Epidermal growth factor receptor in breast carcinoma: association between gene copy number and mutations.

21 January 2018

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Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer

21 January 2018

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Trastuzumab emtansine for HER2-positive advanced breast cancer

21 January 2018

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10.1517/14656566.2013.779672

21 January 2018

Identifiers

DOI

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25 February 2020

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