Effect-directed analysis: Current status and future challenges (Q58815837)

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Jung-Suk Lee

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Jong-Hyeon Lee

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Jong Seong Khim

Ocean science journal : OSJ

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publication date

September 2016

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published in

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volume

51

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issue

3

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page(s)

413-433

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cites work

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Effect-directed analysis of contaminated sediments with partition-based dosing using green algae cell multiplication inhibition

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Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds

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Identification of photosynthesis inhibitors of pelagic marine algae using 96-well plate microfractionation for enhanced throughput in effect-directed analysis.

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Effect-directed fractionation and identification of cytochrome p4501A-inducing halogenated aromatic hydrocarbons in a contaminated sediment

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Effect-directed analysis: a promising tool for the identification of organic toxicants in complex mixtures?

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Sequential fractionation procedure for the identification of potentially cytochrome P4501A-inducing compounds

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Effect-directed identification of oxygen and sulfur heterocycles as major polycyclic aromatic cytochrome P4501A-inducers in a contaminated sediment

21 January 2018

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Effect-directed analysis of mutagens and ethoxyresorufin-o-deethylase inducers in aquatic sediments

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How to confirm identified toxicants in effect-directed analysis

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Effects-directed analysis (EDA) and toxicity identification evaluation (TIE): Complementary but different approaches for diagnosing causes of environmental toxicity

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Effect-directed analysis of endocrine-disrupting compounds in multi-contaminated sediment: identification of novel ligands of estrogen and pregnane X receptors.

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Differences in activation of aryl hydrocarbon receptors of white sturgeon relative to lake sturgeon are predicted by identities of key amino acids in the ligand binding domain

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In vitro bioassays for detecting dioxin-like activity--application potentials and limits of detection, a review

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Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos.

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Integrated biological-chemical approach for the isolation and selection of polyaromatic mutagens in surface waters

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Cell bioassays for detection of aryl hydrocarbon (AhR) and estrogen receptor (ER) mediated activity in environmental samples

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Identification of toxicants from marine sediment using effect-directed analysis

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Toxicity profiling: An integrated effect-based tool for site-specific sediment quality assessment

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Effect of ozonation on the estrogenicity and androgenicity of oil sands process-affected water

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Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production

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Are in vitro methods for the detection of endocrine potentials in the aquatic environment predictive for in vivo effects? Outcomes of the Projects SchussenAktiv and SchussenAktivplus in the Lake Constance Area, Germany

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Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect-directed analysis

21 January 2018

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Cell bioassays for detection of aryl hydrocarbon (AhR) and estrogen receptor (ER) mediated activity in environmental samples.

21 January 2018

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Assessment of the effects of chemicals on the expression of ten steroidogenic genes in the H295R cell line using real-time PCR.

21 January 2018

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Endocrine disruption of water and sediment extracts in a non-radioactive dot blot/RNAse protection-assay using isolated hepatocytes of rainbow trout

21 January 2018

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AhR-mediated potency of sediments and soils in estuarine and coastal areas of the Yellow Sea region: a comparison between Korea and China.

21 January 2018

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Instrumental and bioanalytical measures of dioxin-like compounds and activities in sediments of the Pohang Area, Korea

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Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill.

21 January 2018

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Identification of estrogenic compounds in fish bile using bioassay-directed fractionation

21 January 2018

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Effect-directed analysis of contaminated sediment from the wastewater canal in Pancevo industrial area, Serbia.

21 January 2018

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Characterization and Distribution of Trace Organic Contaminants in Sediment from Masan Bay, Korea. 1. Instrumental Analysis

21 January 2018

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Characterization and Distribution of Trace Organic Contaminants in Sediment from Masan Bay, Korea. 2. In Vitro Gene Expression Assays

21 January 2018

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Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry

21 January 2018

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Polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs) and 2,3,7,8-TCDD equivalents (TEQs) in sediment from the Hyeongsan River, Korea

21 January 2018

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LC-high resolution MS in environmental analysis: from target screening to the identification of unknowns

21 January 2018

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Toxicity testing in the 21st century: a vision and a strategy

21 January 2018

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Development of a dynamic delivery method for in vitro bioassays

21 January 2018

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Automated fractionation procedure for polycyclic aromatic compounds in sediment extracts on three coupled normal-phase high-performance liquid chromatography columns

21 January 2018

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Exposure time-dependent effects on the relative potencies and additivity of PAHs in the Ah receptor-based H4IIE-luc bioassay

21 January 2018

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Time-dependent relative potency factors for polycyclic aromatic hydrocarbons and their derivatives in the H4IIE-luc bioassay

21 January 2018

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Revised relative potency values for PCDDs, PCDFs, and non-ortho-substituted PCBs for the optimized H4IIE-luc in vitro bioassay

21 January 2018

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Measured and predicted affinities of binding and relative potencies to activate the AhR of PAHs and their alkylated analogues.

21 January 2018

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Effect-directed analysis of municipal landfill soil reveals novel developmental toxicants in the zebrafish Danio rerio.

21 January 2018

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Effect-directed investigation and interactive effect of organic toxicants in landfill leachates combining Microtox test with RP-HPLC fractionation and GC/MS analysis

21 January 2018

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Thyroid hormone disrupting activities of sediment from the Guanting Reservoir, Beijing, China.

21 January 2018

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PAH-CALUX, an optimized bioassay for AhR-mediated hazard identification of polycyclic aromatic hydrocarbons (PAHs) as individual compounds and in complex mixtures

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Identification of tetrabromobisphenol A diallyl ether as an emerging neurotoxicant in environmental samples by bioassay-directed fractionation and HPLC-APCI-MS/MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Chemometrics-assisted effect-directed analysis of crude and refined oil using comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Use of effect-directed analysis for the identification of organic toxicants in surface flow constructed wetland sediments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Characterizing field sediments from three European river basins with special emphasis on endocrine effects - A recommendation for Potamopyrgus antipodarum as test organism

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Effect directed analysis and mixture effects of estrogenic compounds in a sediment of the river Elbe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Effect-directed analysis of sediment-associated algal toxicants at selected hot spots in the river Elbe basin with a special focus on bioaccessibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Identification of thyroid receptor ant/agonists in water sources using mass balance analysis and monte carlo simulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Blood plasma sample preparation method for the assessment of thyroid hormone-disrupting potency in effect-directed analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Effect-directed analysis to explore the polar bear exposome: identification of thyroid hormone disrupting compounds in plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Identification and quantification of estrogen receptor agonists in wastewater effluents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Effect-directed identification of naphthenic acids as important in vitro xeno-estrogens and anti-androgens in North sea offshore produced water discharges

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Validation of the CALUX bioassay for PCDD/F analyses in human blood plasma and comparison with GC-HRMS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Rainbow trout cell bioassay-derived relative potencies for halogenated aromatic hydrocarbons: Comparison and sensitivity analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

In vitro response of fish and mammalian cells to complex mixtures of polychlorinated naphthalenes, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Relative potencies of individual polycyclic aromatic hydrocarbons to induce dioxinlike and estrogenic responses in three cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Effect-directed analysis of Ah receptor-mediated activities caused by PAHs in suspended particulate matter sampled in flood events

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Masking effect of anti-androgens on androgenic activity in European river sediment unveiled by effect-directed analysis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Identification strategy for unknown pollutants using high-resolution mass spectrometry: androgen-disrupting compounds identified through effect-directed analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Chemically activated luciferase gene expression (CALUX) cell bioassay analysis for the estimation of dioxin-like activity: critical parameters of the CALUX procedure that impact assay results

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4

Challenges in effect-directed analysis with a focus on biological samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12601-016-0038-4