MERS coronavirus outbreak: Implications for emerging viral infections (Q58595060)

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2 May 2020

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13 July 2022

22 October 2022

MERS coronavirus outbreak: Implications for emerging viral infections (English)

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2 May 2020

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2

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2 May 2020

5

Ziad A Memish

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2 May 2020

4

Jaffar A Al-Tawfiq

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2 May 2020

author name string

Awad Al-Omari

series ordinal

1

1 reference

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2 May 2020

Samer Salih

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3

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2 May 2020

language of work or name

English

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publication date

18 October 2018

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Diagnostic Microbiology and Infectious Disease

2 May 2020

1 March 2019

2 references

13 July 2022

22 October 2022

3 references

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2 May 2020

13 July 2022

22 October 2022

93

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2 May 2020

issue

3

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2 May 2020

page(s)

265-285

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A new virus isolated from the human respiratory tract

2 May 2020

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Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study.

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Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques

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Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013.

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Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs

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Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formation

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Characterization of a novel betacoronavirus related to middle East respiratory syndrome coronavirus in European hedgehogs

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Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS.

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Middle East respiratory syndrome coronavirus in bats, Saudi Arabia

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12 December 2020

Adjunctive therapies and immunomodulating agents for severe influenza.

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12 December 2020

The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists

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12 December 2020

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines

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12 December 2020

Middle East Respiratory Syndrome coronavirus (MERS-CoV) serology in major livestock species in an affected region in Jordan, June to September 2013.

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12 December 2020

Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013.

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Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation

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The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling

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Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective descriptive study

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12 December 2020

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

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12 December 2020

Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection

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Stillbirth during infection with Middle East respiratory syndrome coronavirus

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Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response.

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Spread, circulation, and evolution of the Middle East respiratory syndrome coronavirus

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12 December 2020

Interferon-stimulated genes: a complex web of host defenses

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12 December 2020

Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines.

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12 December 2020

Antibodies against MERS coronavirus in dromedary camels, United Arab Emirates, 2003 and 2013.

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12 December 2020

Serological assays for emerging coronaviruses: challenges and pitfalls

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12 December 2020

A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein.

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12 December 2020

Performance and clinical validation of the RealStar MERS-CoV Kit for detection of Middle East respiratory syndrome coronavirus RNA.

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12 December 2020

Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice

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12 December 2020

Middle East respiratory syndrome coronavirus disease in children

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12 December 2020

Current advancements and potential strategies in the development of MERS-CoV vaccines

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Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein

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Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies.

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Ribavirin and interferon-α2b as primary and preventive treatment for Middle East respiratory syndrome coronavirus: a preliminary report of two cases

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Rooting the phylogenetic tree of middle East respiratory syndrome coronavirus by characterization of a conspecific virus from an African bat

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Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus

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Human-Dromedary Camel Interactions and the Risk of Acquiring Zoonotic Middle East Respiratory Syndrome Coronavirus Infection.

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High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus

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12 December 2020

Development and validation of a rapid immunochromatographic assay for detection of Middle East respiratory syndrome coronavirus antigen in dromedary camels

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12 December 2020

Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus.

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12 December 2020

Protease inhibitors targeting coronavirus and filovirus entry

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12 December 2020

2014 MERS-CoV outbreak in Jeddah--a link to health care facilities

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12 December 2020

Systemic and mucosal immunity in mice elicited by a single immunization with human adenovirus type 5 or 41 vector-based vaccines carrying the spike protein of Middle East respiratory syndrome coronavirus

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12 December 2020

Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease

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12 December 2020

Middle Eastern Respiratory Syndrome Corona Virus (MERS CoV): case reports from a tertiary care hospital in Saudi Arabia

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12 December 2020

Middle East respiratory syndrome coronavirus in children

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12 December 2020

Real-time sequence-validated loop-mediated isothermal amplification assays for detection of Middle East respiratory syndrome coronavirus (MERS-CoV).

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12 December 2020

Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study

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12 December 2020

IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study

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12 December 2020

Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein

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12 December 2020

Development and Evaluation of Novel Real-Time Reverse Transcription-PCR Assays with Locked Nucleic Acid Probes Targeting Leader Sequences of Human-Pathogenic Coronaviruses

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12 December 2020

Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus

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Acute Middle East Respiratory Syndrome Coronavirus: Temporal Lung Changes Observed on the Chest Radiographs of 55 Patients

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Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection

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High proportion of MERS-CoV shedding dromedaries at slaughterhouse with a potential epidemiological link to human cases, Qatar 2014

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12 December 2020

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

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12 December 2020

Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

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12 December 2020

Bat-to-human: spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyond

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12 December 2020

Dromedary Camels and the Transmission of Middle East Respiratory Syndrome Coronavirus (MERS-CoV).

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12 December 2020

Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27

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A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates

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Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease

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Middle East Respiratory Syndrome Coronavirus Superspreading Event Involving 81 Persons, Korea 2015.

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Viral Shedding and Antibody Response in 37 Patients With Middle East Respiratory Syndrome Coronavirus Infection

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12 December 2020

Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome

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12 December 2020

Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol

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12 December 2020

Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets

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12 December 2020

Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels in Nigeria, 2015.

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12 December 2020

Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia

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Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis

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Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Illness in Humans, Saudi Arabia, 2014.

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MERS coronavirus: diagnostics, epidemiology and transmission

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12 December 2020

Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus

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12 December 2020

Renal Complications and Their Prognosis in Korean Patients with Middle East Respiratory Syndrome-Coronavirus from the Central MERS-CoV Designated Hospital

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12 December 2020

Lessons learned from new emerging infectious disease, Middle East Respiratory Syndrome coronavirus outbreak in Korea

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Clinical Implications of 5 Cases of Middle East Respiratory Syndrome Coronavirus Infection in a South Korean Outbreak

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Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses

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12 December 2020

Risk factors for severity and mortality in patients with MERS-CoV: Analysis of publicly available data from Saudi Arabia.

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12 December 2020

3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012

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12 December 2020

Treatment strategies for Middle East respiratory syndrome coronavirus

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12 December 2020

The Evolution of Antiviral Defense Systems

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12 December 2020

Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels

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12 December 2020

Middle East Respiratory Syndrome Coronavirus during Pregnancy, Abu Dhabi, United Arab Emirates, 2013.

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12 December 2020

Notes from the Field: Nosocomial Outbreak of Middle East Respiratory Syndrome in a Large Tertiary Care Hospital--Riyadh, Saudi Arabia, 2015.

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12 December 2020

Identifying determinants of heterogeneous transmission dynamics of the Middle East respiratory syndrome (MERS) outbreak in the Republic of Korea, 2015: a retrospective epidemiological analysis

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12 December 2020

Bioinformatics analysis on molecular mechanism of ribavirin and interferon-α in treating MERS-CoV

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12 December 2020

Infection control and prevention practices implemented to reduce transmission risk of Middle East respiratory syndrome-coronavirus in a tertiary care institution in Saudi Arabia.

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12 December 2020

Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)-Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

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12 December 2020

Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).

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12 December 2020

Coronavirus Host Range Expansion and Middle East Respiratory Syndrome Coronavirus Emergence: Biochemical Mechanisms and Evolutionary Perspectives

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Middle East Respiratory Syndrome Coronavirus: What Does a Radiologist Need to Know?

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Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.

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MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic

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MERS-CoV Antibodies in Humans, Africa, 2013-2014.

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Outbreak of Middle East Respiratory Syndrome at Tertiary Care Hospital, Jeddah, Saudi Arabia, 2014

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12 December 2020

Rapid generation of a human monoclonal antibody to combat Middle East respiratory syndrome

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12 December 2020

MERS-CoV diagnosis: An update.

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12 December 2020

Evolutionary Dynamics of MERS-CoV: Potential Recombination, Positive Selection and Transmission

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12 December 2020

Presentation and outcome of Middle East respiratory syndrome in Saudi intensive care unit patients

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12 December 2020

Preventing healthcare-associated transmission of the Middle East Respiratory Syndrome (MERS): Our Achilles heel.

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12 December 2020

Patient characteristics infected with Middle East respiratory syndrome coronavirus infection in a tertiary hospital

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12 December 2020

Middle East respiratory syndrome coronavirus in Al-Madinah City, Saudi Arabia: Demographic, clinical and survival data

1 reference

12 December 2020

Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infection

1 reference

12 December 2020

MERS and the dromedary camel trade between Africa and the Middle East

1 reference

12 December 2020

Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis

1 reference

12 December 2020

Middle East Respiratory Syndrome Coronavirus Infection During Pregnancy: A Report of 5 Cases From Saudi Arabia

1 reference

12 December 2020

Analytical and Clinical Validation of Six Commercial Middle East Respiratory Syndrome Coronavirus RNA Detection Kits Based on Real-Time Reverse-Transcription PCR.

1 reference

12 December 2020

Clinical Presentation and Outcomes of Middle East Respiratory Syndrome in the Republic of Korea

1 reference

12 December 2020

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Is an Important Surface Attachment Factor That Facilitates Entry of Middle East Respiratory Syndrome Coronavirus

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12 December 2020

Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection

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12 December 2020

Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay.

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12 December 2020

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

1 reference

12 December 2020

Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants

1 reference

12 December 2020

CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia

1 reference

12 December 2020

Clinical determinants of the severity of Middle East respiratory syndrome (MERS): a systematic review and meta-analysis

1 reference

12 December 2020

X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design

1 reference

12 December 2020

Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPARγ.

1 reference

12 December 2020

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

1 reference

12 December 2020

Serologic Evidence for MERS-CoV Infection in Dromedary Camels, Punjab, Pakistan, 2012-2015

1 reference

12 December 2020

The role of laboratory diagnostics in emerging viral infections: the example of the Middle East respiratory syndrome epidemic

1 reference

12 December 2020

Cross-sectional surveillance of Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels and other mammals in Egypt, August 2015 to January 2016

1 reference

12 December 2020

Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.

1 reference

12 December 2020

Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.

1 reference

12 December 2020

Evaluation of a Real-Time Reverse Transcription-PCR (RT-PCR) Assay for Detection of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Clinical Samples from an Outbreak in South Korea in 2015.

1 reference

12 December 2020

ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice

1 reference

12 December 2020

Comparative epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia and South Korea.

1 reference

12 December 2020

Longitudinal study of Middle East Respiratory Syndrome coronavirus infection in dromedary camel herds in Saudi Arabia, 2014-2015.

1 reference

12 December 2020

Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses.

1 reference

12 December 2020

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

1 reference

12 December 2020

A review of candidate therapies for Middle East respiratory syndrome from a molecular perspective.

1 reference

12 December 2020

Histopathology of Middle East respiratory syndrome coronovirus (MERS-CoV) infection - clinicopathological and ultrastructural study.

1 reference

12 December 2020

Assessing the Detection of Middle East Respiratory Syndrome Coronavirus IgG in Suspected and Proven Cases of Middle East Respiratory Syndrome Coronavirus Infection

1 reference

12 December 2020

A Novel Dynamic Model Describing the Spread of the MERS-CoV and the Expression of Dipeptidyl Peptidase 4.

1 reference

12 December 2020

Structural insights into the Middle East respiratory syndrome coronavirus 4a protein and its dsRNA binding mechanism

1 reference

12 December 2020

Inclusion of MERS-spike protein ELISA in algorithm to determine serologic evidence of MERS-CoV infection

1 reference

12 December 2020

Identification of a Novel Inhibitor against Middle East Respiratory Syndrome Coronavirus

1 reference

12 December 2020

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.

1 reference

12 December 2020

Characterization of novel monoclonal antibodies against the MERS-coronavirus spike protein and their application in species-independent antibody detection by competitive ELISA.

1 reference

12 December 2020

DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients.

1 reference

12 December 2020

Development of Middle East Respiratory Syndrome Coronavirus vaccines - advances and challenges.

1 reference

12 December 2020

Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus.

1 reference

12 December 2020

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

1 reference

12 December 2020

Corticosteroid Therapy for Critically Ill Patients with the Middle East Respiratory Syndrome

1 reference

12 December 2020

A recombinant VSV-vectored MERS-CoV vaccine induces neutralizing antibody and T cell responses in rhesus monkeys after single dose immunization

1 reference

12 December 2020

Estimating survival rates in MERS-CoV patients 14 and 45 days after experiencing symptoms and determining the differences in survival rates by demographic data, disease characteristics and regions: a worldwide study.

1 reference

12 December 2020

MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape.

1 reference

12 December 2020

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.

1 reference

12 December 2020

Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen.

1 reference

12 December 2020

MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells.

1 reference

12 December 2020

Unusual presentation of Middle East respiratory syndrome coronavirus leading to a large outbreak in Riyadh during 2017.

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus: risk factors and determinants of primary, household, and nosocomial transmission.

1 reference

12 December 2020

MERS transmission and risk factors: a systematic review.

1 reference

12 December 2020

Heterologous prime-boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory syndrome coronavirus.

1 reference

12 December 2020

Distribution and absence of generalized lesions in mice following single dose intramuscular inoculation of the vaccine candidate MVA-MERS-S

1 reference

12 December 2020

Effect of interferon alpha and cyclosporine treatment separately and in combination on Middle East Respiratory Syndrome Coronavirus (MERS-CoV) replication in a human in-vitro and ex-vivo culture model.

1 reference

12 December 2020

Ultrapotent Human Neutralizing Antibody Repertoires Against Middle East Respiratory Syndrome Coronavirus From a Recovered Patient

1 reference

12 December 2020

10.1016/J.DIAGMICROBIO.2018.10.011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30413355%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30413355%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

1 reference