Age-related deregulation of TDP-43 after stroke enhances NF-κB-mediated inflammation and neuronal damage (Q58566479)

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2 May 2020

title

Age-related deregulation of TDP-43 after stroke enhances NF-κB-mediated inflammation and neuronal damage (English)

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2 May 2020

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4

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2 May 2020

Jasna Kriz

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2 May 2020

author name string

Sai Sampath Thammisetty

1

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2 May 2020

Jordi Pedragosa

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2 May 2020

Yuan Cheng Weng

3

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2 May 2020

Anna Planas

5

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2 May 2020

language of work or name

English

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publication date

9 November 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30413172%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neuroinflammation

2 May 2020

published in

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2 May 2020

volume

15

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2 May 2020

issue

1

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2 May 2020

page(s)

312

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Creative Commons Attribution 4.0 International

2 May 2020

copyright license

start time

9 November 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6230239/fullTextXML

inferred from PubMed Central ID database lookup

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Stroke: how large a public health problem, and how can the neurologist help?

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Structural diversity and functional implications of the eukaryotic TDP gene family

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Toll-like receptor signalling

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A subcellular prefractionation protocol for minute amounts of mammalian cell cultures and tissue.

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

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Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.

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12 December 2020

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

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12 December 2020

TDP-43: a novel neurodegenerative proteinopathy

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12 December 2020

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

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12 December 2020

Live imaging of neuroinflammation reveals sex and estrogen effects on astrocyte response to ischemic injury.

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12 December 2020

Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation

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12 December 2020

TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression

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12 December 2020

Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells

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12 December 2020

Live imaging of Toll-like receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation.

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TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis.

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Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

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The molecular links between TDP-43 dysfunction and neurodegeneration

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Epidemiological studies of the effect of stroke on incident dementia: a systematic review

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Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update

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Multimodal microglia imaging of fiber tracts in acute subcortical stroke

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TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

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12 December 2020

Biochemical and histopathological alterations in TAR DNA-binding protein-43 after acute ischemic stroke in rats

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12 December 2020

Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments

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12 December 2020

Accumulation of dietary docosahexaenoic acid in the brain attenuates acute immune response and development of postischemic neuronal damage.

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12 December 2020

Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease

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12 December 2020

Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways

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12 December 2020

Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans

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12 December 2020

The metabolic footprint of aging in mice

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12 December 2020

Galectin-3 is required for resident microglia activation and proliferation in response to ischemic injury.

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Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury.

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Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

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Preclinical models of stroke in aged animals with or without comorbidities: role of neuroinflammation.

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Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins

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Neuroprotective effects of rhynchophylline against ischemic brain injury via regulation of the Akt/mTOR and TLRs signaling pathways.

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Astrocytic metabolic and inflammatory changes as a function of age.

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The Role of TDP-43 in Alzheimer's Disease

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Incidence and extent of TDP-43 accumulation in aging human brain

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Inflammation Induces TDP-43 Mislocalization and Aggregation

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Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology

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12 December 2020

Estrogen receptors alpha mediates postischemic inflammation in chronically estrogen-deprived mice

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Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration.

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12 December 2020

Live imaging of the innate immune response in neonates reveals differential TLR2 dependent activation patterns in sterile inflammation and infection

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Brain Response to Injuries: When Microglia Go Sexist

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12 December 2020

10.1186/S12974-018-1350-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30413172%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30413172%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

PubMed publication ID

30413172

1 reference