Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation (Q58087435)

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20 March 2020

title

Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation (English)

1 reference

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hypertrophic cardiomyopathy

20 March 2020

main subject

1 reference

7

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20 March 2020

Carolyn Ho

9

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20 March 2020

Jolanda van der Velden

12

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E. Rosalie Witjas-Paalberends

20 March 2020

1

object named as

E Rosalie Witjas-Paalberends

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20 March 2020

4

Nicoletta Piroddi

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20 March 2020

3

Beatrice Scellini

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20 March 2020

6

Chiara Tesi

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20 March 2020

11

Corrado Poggesi

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20 March 2020

5

Judith Montag

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20 March 2020

10

Theresia Kraft

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20 March 2020

author name string

Claudia Ferrara

2

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20 March 2020

Michelle Michels

8

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20 March 2020

language of work or name

English

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publication date

13 June 2014

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20 March 2020

published in

Journal of Physiology

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20 March 2020

volume

592

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20 March 2020

page(s)

3257-3272

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20 March 2020

issue

15

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Effects of chronic atrial fibrillation on active and passive force generation in human atrial myofibrils.

20 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

The familial hypertrophic cardiomyopathy-associated myosin mutation R403Q accelerates tension generation and relaxation of human cardiac myofibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Effect of Ca2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Allele-specific gene expression differences in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Oxidation of myofibrillar proteins in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Skeletal muscle expression and abnormal function of beta-myosin in hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Progress with genetic cardiomyopathies: screening, counseling, and testing in dilated, hypertrophic, and arrhythmogenic right ventricular dysplasia/cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Unequal expression of NF1 alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Abnormal contractile properties of muscle fibers expressing beta-myosin heavy chain gene mutations in patients with hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Species- and age-dependent changes in the relative amounts of cardiac myosin isoenzymes in mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Modifier genes for hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Myosin isoenzymes in normal and hypertrophied human ventricular myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Myocardial contraction is 5-fold more economical in ventricular than in atrial human tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

R403Q and L908V mutant beta-cardiac myosin from patients with familial hypertrophic cardiomyopathy exhibit enhanced mechanical performance at the single molecule level

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Sarcomeric determinants of striated muscle relaxation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Myofibrillar ATPase activity and mechanical performance of skinned fibres from rabbit psoas muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Structural interpretation of the mutations in the beta-cardiac myosin that have been implicated in familial hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Functional analysis of the mutations in the human cardiac beta-myosin that are responsible for familial hypertrophic cardiomyopathy. Implication for the clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Determination of left ventricular mass by echocardiography in a normal population: effect of age and sex in addition to body size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Force kinetics and individual sarcomere dynamics in cardiac myofibrils after rapid ca(2+) changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Relaxation kinetics following sudden Ca(2+) reduction in single myofibrils from skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Protein kinase A does not alter economy of force maintenance in skinned rat cardiac trabeculae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Unequal allelic expression of wild-type and mutated β-myosin in familial hypertrophic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

The R403Q myosin mutation implicated in familial hypertrophic cardiomyopathy causes disorder at the actomyosin interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2014.274571

Functional consequences of mutations in the smooth muscle myosin heavy chain at sites implicated in familial hypertrophic cardiomyopathy

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146374

Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction

30 November 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146374

Point mutations in human beta cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: an ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutations display normal

30 November 2018

1 reference

12 December 2020

Isometric tension and mutant myosin heavy chain content in single skeletal myofibers from hypertrophic cardiomyopathy patients

1 reference

12 December 2020

The in vitro motility activity of beta-cardiac myosin depends on the nature of the beta-myosin heavy chain gene mutation in hypertrophic cardiomyopathy

1 reference

12 December 2020

Variability in the ratio of mutant to wildtype myosin heavy chain present in the soleus muscle of patients with familial hypertrophic cardiomyopathy. A new approach for the quantification of mutant to wildtype protein

1 reference

12 December 2020

Pathogenesis of diverse clinical and pathological phenotypes in hypertrophic cardiomyopathy

1 reference

12 December 2020

Quantification of mutant versus wild-type myosin in human muscle biopsies using nano-LC/ESI-MS

1 reference

12 December 2020

Tension generation and relaxation in single myofibrils from human atrial and ventricular myocardium

1 reference

12 December 2020

Impact of temperature on cross-bridge cycling kinetics in rat myocardium

1 reference

12 December 2020