Defective diacylglycerol-induced Ca2+entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets (Q57987856)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22176814%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Defective diacylglycerol-induced Ca2+ entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets (English)

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18 January 2020

7

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Alexander Dietrich

8

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18 January 2020

author name string

G Ramanathan

1

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18 January 2020

S Gupta

2

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18 January 2020

I Thielmann

3

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18 January 2020

I Pleines

4

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18 January 2020

D Varga-Szabo

5

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18 January 2020

F May

6

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B Nieswandt

9

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A Braun

10

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publication date

1 March 2012

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Journal of Thrombosis and Haemostasis

18 January 2020

published in

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18 January 2020

volume

10

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issue

3

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page(s)

419-429

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18 January 2020

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Activation of TRP channels by protons and phosphoinositide depletion in Drosophila photoreceptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Roles of platelet STIM1 and Orai1 in glycoprotein VI- and thrombin-dependent procoagulant activity and thrombus formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

R93W mutation in Orai1 causes impaired calcium influx in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Human TRPC6 expressed in HEK 293 cells forms non-selective cation channels with limited Ca2+ permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca(2+) entry pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Increased vascular smooth muscle contractility in TRPC6-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Flow cytometric detection of activated mouse integrin alphaIIbbeta3 with a novel monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Rac1 is essential for phospholipase C-gamma2 activation in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Protein kinase C-dependent phosphorylation of transient receptor potential canonical 6 (TRPC6) on serine 448 causes channel inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Intracellular Ca2+ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP3 receptor and SERCA3 in human platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Store-operated Ca2+ entry in platelets occurs independently of transient receptor potential (TRP) C1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Platelet senescence is regulated by an internal timer, not damage inflicted by hits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Programmed anuclear cell death delimits platelet life span.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Kv1.3 is the exclusive voltage-gated K+ channel of platelets and megakaryocytes: roles in membrane potential, Ca2+ signalling and platelet count

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Primary and secondary agonists can use P2X(1) receptors as a major pathway to increase intracellular Ca(2+) in the human platelet

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Calcium signaling in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Expression of transient receptor potential mRNA isoforms and Ca(2+) influx in differentiating human stem cells and platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Protein kinase Ctheta negatively regulates store-independent Ca2+ entry and phosphatidylserine exposure downstream of glycoprotein VI in platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Phorbol ester-evoked Ca2+ signaling in human platelets is via autocrine activation of P(2X1) receptors, not a novel non-capacitative Ca2+ entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Protein kinase C activates non-capacitative calcium entry in human platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

Expression profiling and electrophysiological studies suggest a major role for Orai1 in the store-operated Ca2+ influx pathway of platelets and megakaryocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04596.X

10.1111/J.1538-7836.2011.04596.X

21 January 2018

Identifiers

DOI

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18 January 2020

1 reference