Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma (Q57591227)

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9 December 2019

title

Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma (English)

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9 December 2019

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1

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9 December 2019

Charis Eng

6

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9 December 2019

5

Nicholas K Hayward

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9 December 2019

author name string

Xiao-Ping Zhou

2

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9 December 2019

Sandra Pavey

4

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9 December 2019

Margaret C Cummings

3

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publication date

1 May 2002

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International Journal of Cancer

9 December 2019

language of work or name

English

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number of pages

5

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based on heuristic

inferred from page(s)

published in

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9 December 2019

volume

99

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9 December 2019

issue

1

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9 December 2019

page(s)

63-67

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Localization of the gene for Cowden disease to chromosome 10q22–23

9 December 2019

cites work

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Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

21 January 2018

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The role of MMAC1 mutations in early-onset breast cancer: causative in association with Cowden syndrome and excluded in BRCA1-negative cases.

21 January 2018

1 reference

Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation

21 January 2018

1 reference

PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome

21 January 2018

1 reference

Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis

21 January 2018

1 reference

Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes

21 January 2018

1 reference

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

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PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

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PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies

21 January 2018

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PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model

21 January 2018

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PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways

21 January 2018

1 reference

Growth factor and cytogenetic abnormalities in cultured nevi and malignant melanomas

21 January 2018

1 reference

Variation in cancer risks, by mutation position, in BRCA2 mutation carriers

21 January 2018

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Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines

21 January 2018

1 reference

Identification of PTEN mutations in metastatic melanoma specimens

21 January 2018

1 reference

Epigenetic PTEN silencing in malignant melanomas without PTEN mutation

21 January 2018

1 reference

p53 expression and risk factors for cutaneous melanoma: a case-control study.

21 January 2018

1 reference

Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast

21 January 2018

1 reference

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

21 January 2018

1 reference

Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells

21 January 2018

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Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors

21 January 2018

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Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas

21 January 2018

1 reference

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

21 January 2018

1 reference

Regulation of PTEN transcription by p53

21 January 2018

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Allelic loss of 10q23, the PTEN tumour suppressor gene locus, in Barrett's oesophagus-associated adenocarcinoma

21 January 2018

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10q deletions in metastatic cutaneous melanoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.10294

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9 December 2019

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