ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication (Q57465855)

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28 April 2020

title

ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication (English)

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28 April 2020

7

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28 April 2020

Anthony Leung

8

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28 April 2020

4

Age Utt

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28 April 2020

9

Diane E Griffin

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28 April 2020

author name string

Rachy Abraham

1

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28 April 2020

Debra Hauer

2

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28 April 2020

Robert Lyle McPherson

3

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28 April 2020

Ilsa T Kirby

5

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28 April 2020

Michael S Cohen

6

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28 April 2020

language of work or name

English

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publication date

15 October 2018

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Proceedings of the National Academy of Sciences of the United States of America

28 April 2020

published in

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volume

115

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28 April 2020

page(s)

E10457-E10466

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issue

44

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describes a project that uses

28 April 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6217424/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

1 reference

12 December 2020

Computer-assisted assignment of functional domains in the nonstructural polyprotein of hepatitis E virus: delineation of an additional group of positive-strand RNA plant and animal viruses

1 reference

12 December 2020

Putative papain-related thiol proteases of positive-strand RNA viruses. Identification of rubi- and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi-, alpha- and coronaviruses

1 reference

12 December 2020

Phosphorylation of Sindbis virus nsP3 in vivo and in vitro

1 reference

12 December 2020

Processing the nonstructural polyproteins of sindbis virus: nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in trans

1 reference

12 December 2020

Alphavirus RNA replicase is located on the cytoplasmic surface of endosomes and lysosomes

1 reference

12 December 2020

Semliki Forest virus-specific non-structural protein nsP3 is a phosphoprotein

1 reference

12 December 2020

1 reference

12 December 2020

Short-lived minus-strand polymerase for Semliki Forest virus.

1 reference

12 December 2020

Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis

1 reference

12 December 2020

Evaluation of the spinal cord neuron X neuroblastoma hybrid cell line NSC-34 as a model for neurotoxicity testing.

1 reference

12 December 2020

The alphaviruses: gene expression, replication, and evolution

1 reference

12 December 2020

Genetic analysis of the nsP3 region of Sindbis virus: evidence for roles in minus-strand and subgenomic RNA synthesis

1 reference

12 December 2020

Alphavirus nsP3 functions to form replication complexes transcribing negative-strand RNA

1 reference

12 December 2020

Regulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesis

1 reference

12 December 2020

Temporal changes in chromatin, intracellular calcium, and poly(ADP-ribose) polymerase during Sindbis virus-induced apoptosis of neuroblastoma cells

1 reference

12 December 2020

Replicase complex genes of Semliki Forest virus confer lethal neurovirulence

1 reference

12 December 2020

Elimination of phosphorylation sites of Semliki Forest virus replicase protein nsP3.

1 reference

12 December 2020

RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization

1 reference

12 December 2020

Rapid activation of poly(ADP-ribose) polymerase contributes to Sindbis virus and staurosporine-induced apoptotic cell death

1 reference

12 December 2020

Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein

1 reference

12 December 2020

The global emergence/resurgence of arboviral diseases as public health problems

1 reference

12 December 2020

Alphavirus minus-strand synthesis and persistence in mouse embryo fibroblasts derived from mice lacking RNase L and protein kinase R.

1 reference

12 December 2020

The RasGAP-associated endoribonuclease G3BP assembles stress granules

1 reference

12 December 2020

Amino acid mutations in the replicase protein nsP3 of Semliki Forest virus cumulatively affect neurovirulence

1 reference

12 December 2020

Expression of the zinc-finger antiviral protein inhibits alphavirus replication

1 reference

12 December 2020

Functional analysis of nsP3 phosphoprotein mutants of Sindbis virus

1 reference

12 December 2020

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

1 reference

12 December 2020

Inhibition of Transcription and Translation in Sindbis Virus-Infected Cells

1 reference

12 December 2020

ADP-ribose-1"-monophosphatase: a conserved coronavirus enzyme that is dispensable for viral replication in tissue culture

1 reference

12 December 2020

Formation of nsP3-Specific Protein Complexes during Sindbis Virus Replication

1 reference

12 December 2020

Sindbis virus nonstructural protein nsP2 is cytotoxic and inhibits cellular transcription

1 reference

12 December 2020

Tracking and elucidating alphavirus-host protein interactions

1 reference

12 December 2020

Role of the Amphipathic Peptide of Semliki Forest Virus Replicase Protein nsP1 in Membrane Association and Virus Replication

1 reference

12 December 2020

Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations

1 reference

12 December 2020

Identification and characterization of interferon-induced proteins that inhibit alphavirus replication

1 reference

12 December 2020

The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response

1 reference

12 December 2020

Mammalian ADP-ribosyltransferases and ADP-ribosylhydrolases

1 reference

12 December 2020

Different types of nsP3-containing protein complexes in Sindbis virus-infected cells

1 reference

12 December 2020

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

1 reference

12 December 2020

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

1 reference

12 December 2020

Mouse hepatitis virus liver pathology is dependent on ADP-ribose-1''-phosphatase, a viral function conserved in the alpha-like supergroup

1 reference

12 December 2020

SUnSET, a nonradioactive method to monitor protein synthesis.

1 reference

12 December 2020

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

1 reference

12 December 2020

The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice

1 reference

12 December 2020

Neurological complications of Chikungunya virus infection

1 reference

12 December 2020

Interaction of Sindbis virus non-structural protein 3 with poly(ADP-ribose) polymerase 1 in neuronal cells

1 reference

12 December 2020

Endoribonucleases--enzymes gaining spotlight in mRNA metabolism.

1 reference

12 December 2020

Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication

1 reference

12 December 2020

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling

1 reference

12 December 2020

Pathogen-mediated posttranslational modifications: A re-emerging field

1 reference

12 December 2020

Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography

1 reference

12 December 2020

Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cells

1 reference

12 December 2020

The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses

1 reference

12 December 2020

Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm.

1 reference

12 December 2020

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

1 reference

12 December 2020

The role of posttranslational modifications in the assembly of stress granules

1 reference

12 December 2020

Macromolecular assembly-driven processing of the 2/3 cleavage site in the alphavirus replicase polyprotein

1 reference

12 December 2020

SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication

1 reference

12 December 2020

Replication of alphaviruses: a review on the entry process of alphaviruses into cells

1 reference

12 December 2020

Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoprotein

1 reference

12 December 2020

Evasion of the innate immune response: the Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II

1 reference

12 December 2020

New PARP gene with an anti-alphavirus function

1 reference

12 December 2020

Large G3BP-induced granules trigger eIF2α phosphorylation

1 reference

12 December 2020

Chikungunya virus nsP3 blocks stress granule assembly by recruitment of G3BP into cytoplasmic foci

1 reference

12 December 2020

Structural and functional insights into alphavirus polyprotein processing and pathogenesis

1 reference

12 December 2020

O'nyong nyong virus molecular determinants of unique vector specificity reside in non-structural protein 3.

1 reference

12 December 2020

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation

1 reference

12 December 2020

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases.

1 reference

12 December 2020

Hypervariable domain of nonstructural protein nsP3 of Venezuelan equine encephalitis virus determines cell-specific mode of virus replication

1 reference

12 December 2020

Interferon-stimulated poly(ADP-Ribose) polymerases are potent inhibitors of cellular translation and virus replication

1 reference

12 December 2020

Rapid evolution of PARP genes suggests a broad role for ADP-ribosylation in host-virus conflicts

1 reference

12 December 2020

The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis

1 reference

12 December 2020

The stress granule protein G3BP1 recruits protein kinase R to promote multiple innate immune antiviral responses

1 reference

12 December 2020

Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2

1 reference

12 December 2020

Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication

1 reference

12 December 2020

Role of zinc-finger anti-viral protein in host defense against Sindbis virus

1 reference

12 December 2020

Chikungunya virus and the global spread of a mosquito-borne disease

1 reference

12 December 2020

Alphavirus RNA synthesis and non-structural protein functions

1 reference

12 December 2020

Differences in Processing Determinants of Nonstructural Polyprotein and in the Sequence of Nonstructural Protein 3 Affect Neurovirulence of Semliki Forest Virus

1 reference

12 December 2020

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

1 reference

12 December 2020

Mosquito Rasputin interacts with chikungunya virus nsP3 and determines the infection rate in Aedes albopictus

1 reference

12 December 2020

Crystal structure of the G3BP2 NTF2-like domain in complex with a canonical FGDF motif peptide

1 reference

12 December 2020

Sphingosine kinase 2 is a chikungunya virus host factor co-localized with the viral replication complex

1 reference

12 December 2020

RNA Replication and Membrane Modification Require the Same Functions of Alphavirus Nonstructural Proteins

1 reference

12 December 2020

Macrodomains: Structure, Function, Evolution, and Catalytic Activities

1 reference

12 December 2020

Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein

1 reference

12 December 2020

Virus-Host Interactions and the ARTD/PARP Family of Enzymes

1 reference

12 December 2020

Neurological Sequelae Resulting from Encephalitic Alphavirus Infection

1 reference

12 December 2020

NEDDylation promotes stress granule assembly

1 reference

12 December 2020

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication

1 reference

12 December 2020

Viral Macro Domains Reverse Protein ADP-Ribosylation.

1 reference

12 December 2020

New World and Old World Alphaviruses Have Evolved to Exploit Different Components of Stress Granules, FXR and G3BP Proteins, for Assembly of Viral Replication Complexes

1 reference

12 December 2020

Arginine Demethylation of G3BP1 Promotes Stress Granule Assembly

1 reference

12 December 2020

Casein Kinase 2 Is Linked to Stress Granule Dynamics through Phosphorylation of the Stress Granule Nucleating Protein G3BP1.

1 reference

12 December 2020

The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

1 reference

12 December 2020

Alphavirus polymerase and RNA replication

1 reference

12 December 2020

ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence

1 reference

12 December 2020

The conserved macrodomains of the non-structural proteins of Chikungunya virus and other pathogenic positive strand RNA viruses function as mono-ADP-ribosylhydrolases

1 reference

12 December 2020

Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1.

1 reference

12 December 2020

Generation and Characterization of Recombinant Antibody-like ADP-Ribose Binding Proteins.

1 reference

12 December 2020

Interferon regulated gene (IRG) expression-signature in a mouse model of chikungunya virus neurovirulence

1 reference

12 December 2020

Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses.

1 reference

12 December 2020

Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis.

1 reference

12 December 2020

Interactions of Alphavirus nsP3 Protein with Host Proteins.

1 reference

12 December 2020

The Regulation of Translation in Alphavirus-Infected Cells.

1 reference

12 December 2020

The Enigmatic Alphavirus Non-Structural Protein 3 (nsP3) Revealing Its Secrets at Last.

1 reference

12 December 2020

Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases.

1 reference

12 December 2020

A Chikungunya virus trans-replicase system reveals the importance of delayed non-structural polyprotein processing for efficient replication complex formation in mosquito cells.

1 reference

12 December 2020

Multiple Host Factors Interact with Hypervariable Domain of Chikungunya Virus nsP3 and Determine Viral Replication in Cell-Specific Mode

1 reference

12 December 2020

A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1812130115

1 reference

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28 April 2020

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28 April 2020

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