MYC and DNMT3A-mediated DNA methylation represses microRNA-200b in triple negative breast cancer (Q57458086)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30324719%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

title

MYC and DNMT3A-mediated DNA methylation represses microRNA-200b in triple negative breast cancer (English)

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28 April 2020

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13

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Hong Ren

14

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28 April 2020

author name string

Yamei Pang

1

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28 April 2020

Jian Liu

2

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28 April 2020

Xiang Li

3

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28 April 2020

Guodong Xiao

4

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28 April 2020

Huangzhen Wang

5

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28 April 2020

Ganghua Yang

6

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Yanbo Li

7

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28 April 2020

Shou-Ching Tang

8

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28 April 2020

Sida Qin

9

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28 April 2020

Ning Du

10

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28 April 2020

Henggang Zhang

11

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Dapeng Liu

12

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language of work or name

English

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publication date

16 October 2018

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Journal of Cellular and Molecular Medicine

28 April 2020

published in

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volume

22

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issue

12

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28 April 2020

page(s)

6262-6274

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describes a project that uses

28 April 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6237581/fullTextXML

inferred from PubMed Central ID database lookup

cites work

MicroRNAs: genomics, biogenesis, mechanism, and function

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12 December 2020

Myc represses transcription through recruitment of DNA methyltransferase corepressor

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Triple-negative breast cancer: clinical features and patterns of recurrence

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let-7 regulates self renewal and tumorigenicity of breast cancer cells

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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

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The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

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A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

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12 December 2020

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

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12 December 2020

The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis

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12 December 2020

E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells

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12 December 2020

Transcriptional regulation of Wnt inhibitory factor-1 by Miz-1/c-Myc.

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12 December 2020

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

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12 December 2020

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

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12 December 2020

Triple-Negative Breast Cancer

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12 December 2020

EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells

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12 December 2020

Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis

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12 December 2020

Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status i

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12 December 2020

MYC on the path to cancer

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12 December 2020

CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis.

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A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation

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Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas

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MicroRNA-200 family modulation in distinct breast cancer phenotypes

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MicroRNA-152 targets DNA methyltransferase 1 in NiS-transformed cells via a feedback mechanism

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Tamoxifen represses miR-200 microRNAs and promotes epithelial-to-mesenchymal transition by up-regulating c-Myc in endometrial carcinoma cell lines

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12 December 2020

Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation

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Kindlin 2 promotes breast cancer invasion via epigenetic silencing of the microRNA200 gene family

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12 December 2020

Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state

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12 December 2020

The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

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12 December 2020

c-Myc-mediated epigenetic silencing of MicroRNA-101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma

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12 December 2020

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12 December 2020

MicroRNAs and cancer stem cells: the sword and the shield

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12 December 2020

MiR-200, a new star miRNA in human cancer

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12 December 2020

A regulatory loop involving miR-22, Sp1, and c-Myc modulates CD147 expression in breast cancer invasion and metastasis

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12 December 2020

MicroRNA-200b targets protein kinase Cα and suppresses triple-negative breast cancer metastasis

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12 December 2020

Restoration of miR-101 suppresses lung tumorigenesis through inhibition of DNMT3a-dependent DNA methylation

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12 December 2020

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.

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12 December 2020

DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression

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12 December 2020

DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1.

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12 December 2020

The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy

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MicroRNA-based therapy and breast cancer: A comprehensive review of novel therapeutic strategies from diagnosis to treatment.

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12 December 2020

Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer

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12 December 2020

MYC, Metabolism, and Cancer

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12 December 2020

MiR-208a stimulates the cocktail of SOX2 and β-catenin to inhibit the let-7 induction of self-renewal repression of breast cancer stem cells and formed miR208a/let-7 feedback loop via LIN28 and DICER1

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12 December 2020

Let-7c blocks estrogen-activated Wnt signaling in induction of self-renewal of breast cancer stem cells

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12 December 2020

The insights of Let-7 miRNAs in oncogenesis and stem cell potency

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12 December 2020

Epigenetically deregulated miR-200c is involved in a negative feedback loop with DNMT3a in gastric cancer cells.

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12 December 2020

Direct Interaction of c-Myc with Smad2 and Smad3 to Inhibit TGF-β-Mediated Induction of the CDK Inhibitor p15(Ink4B)

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12 December 2020

Epigenetic regulation of miR-200 as the potential strategy for the therapy against triple-negative breast cancer.

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12 December 2020

Identifiers

DOI

10.1111/JCMM.13916

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28 April 2020

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28 April 2020

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